Primary visual area layer 4 spiny 313862022 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Scnn1a-Tg2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001454
Cell_473465456.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001454
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -72.49 mV
Rheobase Current Interval (0.18906, 0.19066] nA
Threshold Current Interval (0.35156, 0.41016] nA
Bias Current (to -80.00 mV) -0.2372 nA
Testing Temperature 34.0 °C
Stability Interval [-7.8125, 15.0] nA
AP 1-2 Amplitude Drop 18.8148 mV
AP 1 Steady State Amplitude Change N/A mV
AP 1 Amplitude 72.0302 mV
AP 1 Width at Half Height 0.8600 ms
AP 1 Width (Peak To Trough) 5.1200 ms
AP 1 Rate of Change Peak to Trough -17.8507 mV/ms
AP 1 AHP Depth 19.3656 mV
AP2 Amplitude 53.2154 mV
AP2 Width at Half Height 1.0300 ms
AP 2 Width (Peak to Trough) 10.0500 ms
AP 2 Rate of Change Peak to Trough -7.2629 mV/ms
AP 2 AHP Depth 19.7768 mV
AP 1-2 Amplitude Change Percent -26.1208 %
AP 1-2 Half Width Change Percent 19.7674 %
AP 1-2 Rate of Change Peak to Trough Percent Change -59.3132 %
AP 1-2 AHP Depth Percent Change 2.1234 %
Input Resistance 33.5680 MΩ
AP 1 Delay Mean 5.8300 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 548.0300 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 653.3550 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -100.0000 %
Steady State Accommodation Mean -100.0000 %
Accommodation Rate to Steady State N/A %/ms
Accommodation at Steady State Mean N/A %
Accommodation Rate Mean at Steady State N/A ms
ISI CV 5.8779
ISI Median 653.3550 ms
ISI Burst Mean Change 41.0015 %
Spike Rate (Strong Stimulation) 64.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 1.0500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 14.8600 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 14.1000 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2052.1900 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 9515.06 µm2
Number of Stems 9.0
Number of Bifurcations 40.0
Number of Branches 89.0
Overall Width 223.501 µm
Overall Height 538.162 µm
Overall Depth 96.19 µm
Average Diameter 0.511262 µm
Total Length 3639.97 µm
Total Surface 6414.45 µm2
Total Volume 3239.58 µm3
Max Euclidean Distance 492.548 µm
Max Path Distance 569.216 µm
Max Branch Order 9.0
Average Contraction 0.894065
Total Fragmentation 2643.0
Partition Asymmetry 0.52077
Average Rall's Ratio 2.53441
Average Bifurcation Angle Local 63.1796 °
Average Bifurcation Angle Remote 70.545 °
Fractal Dimension 1.03759
Complexity Summary
State Equations 207
Optimal Time-Step 0.01162 ms
Relative Complexity 21.28 HH
Model Size
Sections 89
Compartments 191
State Equations 207
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01162 ms
Optimal Time-Step Error 0.20 %
Optimal Time-Step Benchmark Run Time 21.28 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 0.93 %
Max. Stable Time-Step Benchmark Run Time 30.90 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 14983 Hz
CVODE Steps Per AP -776
CVODE Benchmark Run Time 11.73 HH
Website & Images Copyright NeuroML © 2019 For questions: Contact us Links: Search Test |  ModelDB WS