Primary visual area layer 2/3 aspiny 478107198 Cell

Model Type:
Cell
Neurolex IDs: Visual cortex primary layer 2
Visual cortex primary layer 3
Keywords: Mus musculus, Htr3a-Cre_NO152
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001452
Cell_479234530.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001452
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -78.24 mV
Rheobase Current Interval (0.07851, 0.08011] nA
Threshold Current Interval (0.35156, 0.41016] nA
Bias Current (to -70.00 mV) 0.0643 nA
Testing Temperature 34.0 °C
Stability Interval [-5.0, 15.0] nA
AP 1-2 Amplitude Drop 0.7100 mV
AP 1 Steady State Amplitude Change 0.3557 mV
AP 1 Amplitude 65.8972 mV
AP 1 Width at Half Height 0.5100 ms
AP 1 Width (Peak To Trough) 14.6600 ms
AP 1 Rate of Change Peak to Trough -5.2377 mV/ms
AP 1 AHP Depth 10.8870 mV
AP2 Amplitude 65.1872 mV
AP2 Width at Half Height 0.5200 ms
AP 2 Width (Peak to Trough) 13.3400 ms
AP 2 Rate of Change Peak to Trough -6.1107 mV/ms
AP 2 AHP Depth 16.3295 mV
AP 1-2 Amplitude Change Percent -1.0774 %
AP 1-2 Half Width Change Percent 1.9608 %
AP 1-2 Rate of Change Peak to Trough Percent Change 16.6684 %
AP 1-2 AHP Depth Percent Change 49.9915 %
Input Resistance 111.6309 MΩ
AP 1 Delay Mean 20.1100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 54.3800 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 41.0950 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -33.0874 %
Accommodation Rate Mean at Steady State 49.1891 ms
ISI CV 17.0748
ISI Median 52.0250 ms
ISI Burst Mean Change 39.8308 %
Spike Rate (Strong Stimulation) 41.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 6.3000 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 12.1100 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 15.9950 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2066.6800 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 41.6230 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6543.1 µm2
Number of Stems 8.0
Number of Bifurcations 34.0
Number of Branches 76.0
Overall Width 101.085 µm
Overall Height 127.45 µm
Overall Depth 44.76 µm
Average Diameter 0.401823 µm
Total Length 1786.29 µm
Total Surface 2697.14 µm2
Total Volume 1888.97 µm3
Max Euclidean Distance 104.75 µm
Max Path Distance 138.956 µm
Max Branch Order 7.0
Average Contraction 0.893291
Total Fragmentation 1479.0
Partition Asymmetry 0.439542
Average Rall's Ratio 2.42562
Average Bifurcation Angle Local 80.8065 °
Average Bifurcation Angle Remote 77.8548 °
Fractal Dimension 1.03631
Complexity Summary
State Equations 129
Optimal Time-Step 0.02271 ms
Relative Complexity 12.86 HH
Model Size
Sections 75
Compartments 101
State Equations 129
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02271 ms
Optimal Time-Step Error 1.00 %
Optimal Time-Step Benchmark Run Time 12.86 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 2.41 %
Max. Stable Time-Step Benchmark Run Time 9.12 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 3948 Hz
CVODE Steps Per AP 1222
CVODE Benchmark Run Time 31.05 HH
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