Primary visual area layer 5 aspiny 464212183 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Sst-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001451
Cell_472299363.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001451
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -80.14 mV
Rheobase Current Interval (0.06889, 0.07050] nA
Threshold Current Interval (0.35156, 0.41016] nA
Bias Current (to -70.00 mV) 0.0504 nA
Testing Temperature 34.0 °C
Stability Interval [-3.4375, 15.0] nA
AP 1-2 Amplitude Drop 2.6972 mV
AP 1 Steady State Amplitude Change 2.9488 mV
AP 1 Amplitude 53.0007 mV
AP 1 Width at Half Height 0.5900 ms
AP 1 Width (Peak To Trough) 36.3600 ms
AP 1 Rate of Change Peak to Trough -2.0660 mV/ms
AP 1 AHP Depth 22.1176 mV
AP2 Amplitude 50.3035 mV
AP2 Width at Half Height 0.6000 ms
AP 2 Width (Peak to Trough) 56.3500 ms
AP 2 Rate of Change Peak to Trough -1.2918 mV/ms
AP 2 AHP Depth 22.4883 mV
AP 1-2 Amplitude Change Percent -5.0889 %
AP 1-2 Half Width Change Percent 1.6949 %
AP 1-2 Rate of Change Peak to Trough Percent Change -37.4731 %
AP 1-2 AHP Depth Percent Change 1.6759 %
Input Resistance 189.4789 MΩ
AP 1 Delay Mean 32.2600 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 783.9500 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 749.9750 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -100.0000 %
Steady State Accommodation Mean -100.0000 %
Accommodation Rate to Steady State N/A %/ms
Accommodation at Steady State Mean N/A %
Accommodation Rate Mean at Steady State N/A ms
ISI CV 437.3032
ISI Median 749.9750 ms
ISI Burst Mean Change -0.4563 %
Spike Rate (Strong Stimulation) 21.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 7.4200 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 61.8000 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 54.1000 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2066.4100 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5184.61 µm2
Number of Stems 4.0
Number of Bifurcations 42.0
Number of Branches 88.0
Overall Width 200.967 µm
Overall Height 345.717 µm
Overall Depth 72.73 µm
Average Diameter 0.438578 µm
Total Length 3237.29 µm
Total Surface 4857.86 µm2
Total Volume 1874.36 µm3
Max Euclidean Distance 321.212 µm
Max Path Distance 456.506 µm
Max Branch Order 7.0
Average Contraction 0.861607
Total Fragmentation 2644.0
Partition Asymmetry 0.502966
Average Rall's Ratio 2.435
Average Bifurcation Angle Local 73.3671 °
Average Bifurcation Angle Remote 68.6364 °
Fractal Dimension 1.06379
Complexity Summary
State Equations 211
Optimal Time-Step 0.02141 ms
Relative Complexity 15.81 HH
Model Size
Sections 87
Compartments 183
State Equations 211
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02141 ms
Optimal Time-Step Error 0.47 %
Optimal Time-Step Benchmark Run Time 15.81 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 2.80 %
Max. Stable Time-Step Benchmark Run Time 10.57 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4451 Hz
CVODE Steps Per AP 913
CVODE Benchmark Run Time 30.22 HH
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