Primary visual area layer 5 spiny 480116737 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Rorb-IRES2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001449
Cell_482655070.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001449
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -77.73 mV
Rheobase Current Interval (0.04257, 0.04395] nA
Threshold Current Interval (0.29297, 0.35156] nA
Bias Current (to -70.00 mV) 0.0297 nA
Testing Temperature 34.0 °C
Stability Interval [-0.9375, 15.0] nA
AP 1-2 Amplitude Drop 0.6248 mV
AP 1 Steady State Amplitude Change 3.9823 mV
AP 1 Amplitude 66.5149 mV
AP 1 Width at Half Height 0.9600 ms
AP 1 Width (Peak To Trough) 10.2400 ms
AP 1 Rate of Change Peak to Trough -8.4799 mV/ms
AP 1 AHP Depth 20.3192 mV
AP2 Amplitude 65.8901 mV
AP2 Width at Half Height 0.9700 ms
AP 2 Width (Peak to Trough) 9.6400 ms
AP 2 Rate of Change Peak to Trough -8.9650 mV/ms
AP 2 AHP Depth 20.5322 mV
AP 1-2 Amplitude Change Percent -0.9393 %
AP 1-2 Half Width Change Percent 1.0417 %
AP 1-2 Rate of Change Peak to Trough Percent Change 5.7204 %
AP 1-2 AHP Depth Percent Change 1.0485 %
Input Resistance 181.8809 MΩ
AP 1 Delay Mean 30.7500 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 71.8000 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 43.6300 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -66.6667 %
Steady State Accommodation Mean -66.6667 %
Accommodation Rate to Steady State -0.0911 %/ms
Accommodation at Steady State Mean -88.6602 %
Accommodation Rate Mean at Steady State 350.4442 ms
ISI CV 2.2477
ISI Median 195.5900 ms
ISI Burst Mean Change 12.5700 %
Spike Rate (Strong Stimulation) 19.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 9.8900 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 30.1500 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 20.6350 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2264.9500 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 121.0157 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 8902.73 µm2
Number of Stems 11.0
Number of Bifurcations 38.0
Number of Branches 87.0
Overall Width 230.139 µm
Overall Height 593.074 µm
Overall Depth 82.26 µm
Average Diameter 0.358741 µm
Total Length 4099.41 µm
Total Surface 5210.75 µm2
Total Volume 2700.66 µm3
Max Euclidean Distance 510.966 µm
Max Path Distance 606.807 µm
Max Branch Order 10.0
Average Contraction 0.885511
Total Fragmentation 3436.0
Partition Asymmetry 0.442105
Average Rall's Ratio 2.38
Average Bifurcation Angle Local 74.3141 °
Average Bifurcation Angle Remote 71.5437 °
Fractal Dimension 1.03353
Complexity Summary
State Equations 235
Optimal Time-Step 0.01137 ms
Relative Complexity 24.55 HH
Model Size
Sections 87
Compartments 219
State Equations 235
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01137 ms
Optimal Time-Step Error 0.19 %
Optimal Time-Step Benchmark Run Time 24.55 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 1.14 %
Max. Stable Time-Step Benchmark Run Time 34.89 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 13241 Hz
CVODE Steps Per AP 672
CVODE Benchmark Run Time 36.65 HH
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