Primary visual area layer 5 aspiny 478396248 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Sst-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001448
Cell_479234670.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001448
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -80.93 mV
Rheobase Current Interval (0.05264, 0.05493] nA
Threshold Current Interval (0.52734, 0.58594] nA
Bias Current (to -70.00 mV) 0.0412 nA
Testing Temperature 34.0 °C
Stability Interval [-5.3125, 15.0] nA
AP 1-2 Amplitude Drop 0.9235 mV
AP 1 Steady State Amplitude Change 0.1909 mV
AP 1 Amplitude 51.6696 mV
AP 1 Width at Half Height 0.6600 ms
AP 1 Width (Peak To Trough) 6.4300 ms
AP 1 Rate of Change Peak to Trough -9.5804 mV/ms
AP 1 AHP Depth 9.9324 mV
AP2 Amplitude 50.7461 mV
AP2 Width at Half Height 0.6900 ms
AP 2 Width (Peak to Trough) 21.5300 ms
AP 2 Rate of Change Peak to Trough -2.9878 mV/ms
AP 2 AHP Depth 13.5811 mV
AP 1-2 Amplitude Change Percent -1.7873 %
AP 1-2 Half Width Change Percent 4.5455 %
AP 1-2 Rate of Change Peak to Trough Percent Change -68.8135 %
AP 1-2 AHP Depth Percent Change 36.7351 %
Input Resistance 241.7995 MΩ
AP 1 Delay Mean 55.6500 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 86.2900 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 44.4600 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 12.5000 %
Steady State Accommodation Mean 12.5000 %
Accommodation Rate to Steady State 0.0865 %/ms
Accommodation at Steady State Mean -33.8386 %
Accommodation Rate Mean at Steady State 2.3192 ms
ISI CV 12.5254
ISI Median 45.5850 ms
ISI Burst Mean Change 90.2089 %
Spike Rate (Strong Stimulation) 60.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 17.2600 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 25.3400 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 8.2400 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2147.1500 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 133.4244 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 4757.89 µm2
Number of Stems 6.0
Number of Bifurcations 11.0
Number of Branches 28.0
Overall Width 183.146 µm
Overall Height 366.392 µm
Overall Depth 42.29 µm
Average Diameter 0.381153 µm
Total Length 1828.21 µm
Total Surface 2564.91 µm2
Total Volume 1424.89 µm3
Max Euclidean Distance 299.981 µm
Max Path Distance 353.747 µm
Max Branch Order 3.0
Average Contraction 0.920947
Total Fragmentation 1510.0
Partition Asymmetry 0.545455
Average Rall's Ratio 2.70875
Average Bifurcation Angle Local 66.664 °
Average Bifurcation Angle Remote 59.4177 °
Fractal Dimension 1.01954
Complexity Summary
State Equations 118
Optimal Time-Step 0.02311 ms
Relative Complexity 10.04 HH
Model Size
Sections 28
Compartments 90
State Equations 118
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02311 ms
Optimal Time-Step Error 1.27 %
Optimal Time-Step Benchmark Run Time 10.04 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 2.42 %
Max. Stable Time-Step Benchmark Run Time 7.25 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4216 Hz
CVODE Steps Per AP 1073
CVODE Benchmark Run Time 22.82 HH
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