Primary visual area layer 5 aspiny 478110866 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Htr3a-Cre_NO152
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001447
Cell_479234506.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001447
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -89.91 mV
Rheobase Current Interval (0.03459, 0.03592] nA
Threshold Current Interval (0.28381, 0.34058] nA
Bias Current (to -80.00 mV) 0.0096 nA
Testing Temperature 34.0 °C
Stability Interval [-0.9375, 14.53125] nA
AP 1-2 Amplitude Drop -0.5211 mV
AP 1 Steady State Amplitude Change 2.2568 mV
AP 1 Amplitude 50.4723 mV
AP 1 Width at Half Height 0.8100 ms
AP 1 Width (Peak To Trough) 7.6400 ms
AP 1 Rate of Change Peak to Trough -8.5153 mV/ms
AP 1 AHP Depth 14.5843 mV
AP2 Amplitude 50.9934 mV
AP2 Width at Half Height 0.8200 ms
AP 2 Width (Peak to Trough) 6.6700 ms
AP 2 Rate of Change Peak to Trough -9.7085 mV/ms
AP 2 AHP Depth 13.7624 mV
AP 1-2 Amplitude Change Percent 1.0325 %
AP 1-2 Half Width Change Percent 1.2346 %
AP 1-2 Rate of Change Peak to Trough Percent Change 14.0132 %
AP 1-2 AHP Depth Percent Change -5.6355 %
Input Resistance 1075.2355 MΩ
AP 1 Delay Mean 86.2200 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 125.4700 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 38.6350 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -22.2222 %
Steady State Accommodation Mean -22.2222 %
Accommodation Rate to Steady State -0.0194 %/ms
Accommodation at Steady State Mean -49.0885 %
Accommodation Rate Mean at Steady State 993.5458 ms
ISI CV 5.9043
ISI Median 54.1000 ms
ISI Burst Mean Change -3.1338 %
Spike Rate (Strong Stimulation) 35.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 25.0600 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 44.8400 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 19.1100 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2091.8000 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 917.696 µm2
Number of Stems 3.0
Number of Bifurcations 44.0
Number of Branches 91.0
Overall Width 272.224 µm
Overall Height 820.504 µm
Overall Depth 55.55 µm
Average Diameter 0.413308 µm
Total Length 4139.3 µm
Total Surface 5538.91 µm2
Total Volume 873.253 µm3
Max Euclidean Distance 582.138 µm
Max Path Distance 645.191 µm
Max Branch Order 9.0
Average Contraction 0.908773
Total Fragmentation 3615.0
Partition Asymmetry 0.482265
Average Rall's Ratio 2.26781
Average Bifurcation Angle Local 77.2088 °
Average Bifurcation Angle Remote 54.0443 °
Fractal Dimension 1.02481
Complexity Summary
State Equations 234
Optimal Time-Step 0.01102 ms
Relative Complexity 25.65 HH
Model Size
Sections 92
Compartments 218
State Equations 234
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01102 ms
Optimal Time-Step Error 0.08 %
Optimal Time-Step Benchmark Run Time 25.65 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 0.99 %
Max. Stable Time-Step Benchmark Run Time 35.32 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 11101 Hz
CVODE Steps Per AP 692
CVODE Benchmark Run Time 33.50 HH
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