Primary visual area layer 2/3 aspiny 333604946 Cell

Model Type:
Cell
Neurolex IDs: Visual cortex primary layer 2
Visual cortex primary layer 3
Keywords: Mus musculus, Pvalb-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001445
Cell_472306616.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001445
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -86.86 mV
Rheobase Current Interval (0.24696, 0.24994] nA
Threshold Current Interval (0.70312, 0.76172] nA
Bias Current (to -80.00 mV) 0.0526 nA
Testing Temperature 34.0 °C
Stability Interval [-4.0625, 15.0] nA
AP 1-2 Amplitude Drop -3.6796 mV
AP 1 Steady State Amplitude Change -9.8763 mV
AP 1 Amplitude 38.0938 mV
AP 1 Width at Half Height 0.3400 ms
AP 1 Width (Peak To Trough) 1.6400 ms
AP 1 Rate of Change Peak to Trough -31.1407 mV/ms
AP 1 AHP Depth 12.9769 mV
AP2 Amplitude 41.7734 mV
AP2 Width at Half Height 0.3500 ms
AP 2 Width (Peak to Trough) 1.7700 ms
AP 2 Rate of Change Peak to Trough -31.0507 mV/ms
AP 2 AHP Depth 13.1864 mV
AP 1-2 Amplitude Change Percent 9.6593 %
AP 1-2 Half Width Change Percent 2.9412 %
AP 1-2 Rate of Change Peak to Trough Percent Change -0.2888 %
AP 1-2 AHP Depth Percent Change 1.6145 %
Input Resistance 127.5106 MΩ
AP 1 Delay Mean 15.7000 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 23.0300 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 7.2450 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -26.8328 %
Accommodation Rate Mean at Steady State 20.3767 ms
ISI CV 37.4163
ISI Median 9.4300 ms
ISI Burst Mean Change -2.3192 %
Spike Rate (Strong Stimulation) 1.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 2.7200 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 6.7400 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) N/A ms
Burst 1 ISI SD (Strong Stimulation) N/A ms
Ramp First Spike Time 2021.1600 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 8498.21 µm2
Number of Stems 7.0
Number of Bifurcations 19.0
Number of Branches 45.0
Overall Width 177.045 µm
Overall Height 224.84 µm
Overall Depth 61.57 µm
Average Diameter 0.416863 µm
Total Length 2276.01 µm
Total Surface 3505.39 µm2
Total Volume 2458.38 µm3
Max Euclidean Distance 170.502 µm
Max Path Distance 209.719 µm
Max Branch Order 4.0
Average Contraction 0.918507
Total Fragmentation 1839.0
Partition Asymmetry 0.298246
Average Rall's Ratio 3.73125
Average Bifurcation Angle Local 64.0403 °
Average Bifurcation Angle Remote 66.662 °
Fractal Dimension 1.02565
Complexity Summary
State Equations 144
Optimal Time-Step 0.02592 ms
Relative Complexity 10.70 HH
Model Size
Sections 46
Compartments 116
State Equations 144
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02592 ms
Optimal Time-Step Error 2.73 %
Optimal Time-Step Benchmark Run Time 10.70 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 4.14 %
Max. Stable Time-Step Benchmark Run Time 8.67 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 7683 Hz
CVODE Steps Per AP 1112
CVODE Benchmark Run Time 34.31 HH
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