Primary visual area layer 4 spiny 476087653 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Nr5a1-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001444
Cell_478047816.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001444
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -89.57 mV
Rheobase Current Interval (0.06844, 0.07141] nA
Threshold Current Interval (0.70312, 0.76172] nA
Bias Current (to -80.00 mV) 0.0270 nA
Testing Temperature 34.0 °C
Stability Interval [-2.5, 15.0] nA
AP 1-2 Amplitude Drop 0.9598 mV
AP 1 Steady State Amplitude Change 4.1435 mV
AP 1 Amplitude 67.9634 mV
AP 1 Width at Half Height 0.6400 ms
AP 1 Width (Peak To Trough) 7.7000 ms
AP 1 Rate of Change Peak to Trough -10.8448 mV/ms
AP 1 AHP Depth 15.5415 mV
AP2 Amplitude 67.0036 mV
AP2 Width at Half Height 0.6500 ms
AP 2 Width (Peak to Trough) 8.1000 ms
AP 2 Rate of Change Peak to Trough -10.4223 mV/ms
AP 2 AHP Depth 17.4172 mV
AP 1-2 Amplitude Change Percent -1.4122 %
AP 1-2 Half Width Change Percent 1.5625 %
AP 1-2 Rate of Change Peak to Trough Percent Change -3.8956 %
AP 1-2 AHP Depth Percent Change 12.0693 %
Input Resistance 346.4746 MΩ
AP 1 Delay Mean 41.6300 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 73.9200 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 34.8500 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -33.3333 %
Steady State Accommodation Mean -44.4444 %
Accommodation Rate to Steady State -0.0651 %/ms
Accommodation at Steady State Mean -57.7013 %
Accommodation Rate Mean at Steady State 343.8748 ms
ISI CV 5.0210
ISI Median 68.8200 ms
ISI Burst Mean Change 15.8563 %
Spike Rate (Strong Stimulation) 31.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 14.0500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 25.6200 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 13.3600 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2062.6000 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 4426.73 µm2
Number of Stems 7.0
Number of Bifurcations 26.0
Number of Branches 59.0
Overall Width 171.331 µm
Overall Height 352.963 µm
Overall Depth 78.84 µm
Average Diameter 0.612526 µm
Total Length 2072.76 µm
Total Surface 4325.75 µm2
Total Volume 1852.94 µm3
Max Euclidean Distance 275.622 µm
Max Path Distance 301.913 µm
Max Branch Order 6.0
Average Contraction 0.892612
Total Fragmentation 1711.0
Partition Asymmetry 0.52033
Average Rall's Ratio 2.406
Average Bifurcation Angle Local 62.7199 °
Average Bifurcation Angle Remote 69.238 °
Fractal Dimension 1.02964
Complexity Summary
State Equations 118
Optimal Time-Step 0.01061 ms
Relative Complexity 14.14 HH
Model Size
Sections 60
Compartments 102
State Equations 118
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01061 ms
Optimal Time-Step Error 0.46 %
Optimal Time-Step Benchmark Run Time 14.14 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 2.99 %
Max. Stable Time-Step Benchmark Run Time 18.76 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 11793 Hz
CVODE Steps Per AP 1317
CVODE Benchmark Run Time 24.64 HH
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