Primary visual area layer 5 aspiny 466664172 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Sst-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001442
Cell_478513461.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001442
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -82.42 mV
Rheobase Current Interval (0.03204, 0.03365] nA
Threshold Current Interval (0.35156, 0.41016] nA
Bias Current (to -70.00 mV) 0.0331 nA
Testing Temperature 34.0 °C
Stability Interval [-2.1875, 15.0] nA
AP 1-2 Amplitude Drop -6.1206 mV
AP 1 Steady State Amplitude Change 0.0067 mV
AP 1 Amplitude 45.8318 mV
AP 1 Width at Half Height 0.8800 ms
AP 1 Width (Peak To Trough) 4.8000 ms
AP 1 Rate of Change Peak to Trough -12.6384 mV/ms
AP 1 AHP Depth 14.8324 mV
AP2 Amplitude 51.9524 mV
AP2 Width at Half Height 0.8100 ms
AP 2 Width (Peak to Trough) 3.8100 ms
AP 2 Rate of Change Peak to Trough -19.0497 mV/ms
AP 2 AHP Depth 20.6271 mV
AP 1-2 Amplitude Change Percent 13.3544 %
AP 1-2 Half Width Change Percent -7.9545 %
AP 1-2 Rate of Change Peak to Trough Percent Change 50.7294 %
AP 1-2 AHP Depth Percent Change 39.0681 %
Input Resistance 217.1138 MΩ
AP 1 Delay Mean 47.2300 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 59.8000 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 17.0900 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -53.3333 %
Steady State Accommodation Mean -60.0000 %
Accommodation Rate to Steady State -0.0403 %/ms
Accommodation at Steady State Mean -82.1714 %
Accommodation Rate Mean at Steady State 742.1637 ms
ISI CV 1.1175
ISI Median 40.2600 ms
ISI Burst Mean Change 71.9173 %
Spike Rate (Strong Stimulation) 37.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 15.9300 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 23.8800 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 8.1000 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2116.6900 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 9866.26 µm2
Number of Stems 5.0
Number of Bifurcations 13.0
Number of Branches 31.0
Overall Width 118.526 µm
Overall Height 228.25 µm
Overall Depth 38.84 µm
Average Diameter 0.425278 µm
Total Length 968.382 µm
Total Surface 1882.96 µm2
Total Volume 2613.91 µm3
Max Euclidean Distance 163.26 µm
Max Path Distance 195.761 µm
Max Branch Order 4.0
Average Contraction 0.908616
Total Fragmentation 764.0
Partition Asymmetry 0.564103
Average Rall's Ratio 2.18
Average Bifurcation Angle Local 94.0623 °
Average Bifurcation Angle Remote 67.2814 °
Fractal Dimension 1.02642
Complexity Summary
State Equations 61
Optimal Time-Step 0.01111 ms
Relative Complexity 8.67 HH
Model Size
Sections 31
Compartments 45
State Equations 61
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01111 ms
Optimal Time-Step Error 1.61 %
Optimal Time-Step Benchmark Run Time 8.67 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 4.64 %
Max. Stable Time-Step Benchmark Run Time 12.04 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 14298 Hz
CVODE Steps Per AP 92
CVODE Benchmark Run Time 9.65 HH
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