Primary visual area layer 2/3 aspiny 469753383 Cell

Model Type:
Cell
Neurolex IDs: Visual cortex primary layer 2
Visual cortex primary layer 3
Keywords: Mus musculus, Htr3a-Cre_NO152
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001440
Cell_478513187.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001440
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -92.92 mV
Rheobase Current Interval (0.29160, 0.29457] nA
Threshold Current Interval (0.70312, 0.76172] nA
Bias Current (to -80.00 mV) 0.1251 nA
Testing Temperature 34.0 °C
Stability Interval [-2.1875, 15.0] nA
AP 1-2 Amplitude Drop 18.0563 mV
AP 1 Steady State Amplitude Change 21.0279 mV
AP 1 Amplitude 67.6664 mV
AP 1 Width at Half Height 0.5500 ms
AP 1 Width (Peak To Trough) 3.0800 ms
AP 1 Rate of Change Peak to Trough -29.7863 mV/ms
AP 1 AHP Depth 24.0754 mV
AP2 Amplitude 49.6101 mV
AP2 Width at Half Height 0.7300 ms
AP 2 Width (Peak to Trough) 4.5200 ms
AP 2 Rate of Change Peak to Trough -15.7265 mV/ms
AP 2 AHP Depth 21.4735 mV
AP 1-2 Amplitude Change Percent -26.6843 %
AP 1-2 Half Width Change Percent 32.7273 %
AP 1-2 Rate of Change Peak to Trough Percent Change -47.2024 %
AP 1-2 AHP Depth Percent Change -10.8072 %
Input Resistance 106.1757 MΩ
AP 1 Delay Mean 7.2100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 27.0300 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 20.9600 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -5.9700 %
Accommodation Rate Mean at Steady State 0.0494 ms
ISI CV 59.7874
ISI Median 20.9900 ms
ISI Burst Mean Change 11.5035 %
Spike Rate (Strong Stimulation) 136.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 2.3200 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 9.5200 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 7.3850 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2009.0500 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 73.5653 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 3868.62 µm2
Number of Stems 8.0
Number of Bifurcations 30.0
Number of Branches 68.0
Overall Width 111.897 µm
Overall Height 135.001 µm
Overall Depth 38.73 µm
Average Diameter 0.280602 µm
Total Length 1934.26 µm
Total Surface 2149.87 µm2
Total Volume 1157.71 µm3
Max Euclidean Distance 108.991 µm
Max Path Distance 139.621 µm
Max Branch Order 6.0
Average Contraction 0.906624
Total Fragmentation 1738.0
Partition Asymmetry 0.418889
Average Rall's Ratio 1.43875
Average Bifurcation Angle Local 67.4601 °
Average Bifurcation Angle Remote 68.0204 °
Fractal Dimension 1.02776
Complexity Summary
State Equations 121
Optimal Time-Step 0.00757 ms
Relative Complexity 21.11 HH
Model Size
Sections 67
Compartments 105
State Equations 121
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00757 ms
Optimal Time-Step Error 0.11 %
Optimal Time-Step Benchmark Run Time 21.11 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 0.90 %
Max. Stable Time-Step Benchmark Run Time 39.96 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 9527 Hz
CVODE Steps Per AP 587
CVODE Benchmark Run Time 16.18 HH
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