Primary visual area layer 5 aspiny 330080937 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Pvalb-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001437
Cell_472912177.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001437
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -95.25 mV
Rheobase Current Interval (0.16617, 0.16869] nA
Threshold Current Interval (0.58594, 0.64453] nA
Bias Current (to -80.00 mV) 0.0547 nA
Testing Temperature 34.0 °C
Stability Interval [-2.8125, 15.0] nA
AP 1-2 Amplitude Drop 4.6533 mV
AP 1 Steady State Amplitude Change 4.9251 mV
AP 1 Amplitude 51.1320 mV
AP 1 Width at Half Height 0.3400 ms
AP 1 Width (Peak To Trough) 37.6700 ms
AP 1 Rate of Change Peak to Trough -2.2609 mV/ms
AP 1 AHP Depth 34.0372 mV
AP2 Amplitude 46.4787 mV
AP2 Width at Half Height 0.4100 ms
AP 2 Width (Peak to Trough) 14.7000 ms
AP 2 Rate of Change Peak to Trough -4.6843 mV/ms
AP 2 AHP Depth 22.3805 mV
AP 1-2 Amplitude Change Percent -9.1005 %
AP 1-2 Half Width Change Percent 20.5882 %
AP 1-2 Rate of Change Peak to Trough Percent Change 107.1847 %
AP 1-2 AHP Depth Percent Change -34.2470 %
Input Resistance 323.6804 MΩ
AP 1 Delay Mean 15.2800 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 1092.8300 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 771.1150 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean -100.0000 %
Accommodation Rate to Steady State N/A %/ms
Accommodation at Steady State Mean N/A %
Accommodation Rate Mean at Steady State N/A ms
ISI CV 2.5164
ISI Median 771.1150 ms
ISI Burst Mean Change -56.8762 %
Spike Rate (Strong Stimulation) 4.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 4.1100 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 729.6000 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 469.7150 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2132.6800 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5217.84 µm2
Number of Stems 5.0
Number of Bifurcations 17.0
Number of Branches 39.0
Overall Width 242.415 µm
Overall Height 442.505 µm
Overall Depth 76.27 µm
Average Diameter 0.382732 µm
Total Length 2429.66 µm
Total Surface 3323.04 µm2
Total Volume 1641.32 µm3
Max Euclidean Distance 377.636 µm
Max Path Distance 418.78 µm
Max Branch Order 4.0
Average Contraction 0.91768
Total Fragmentation 1905.0
Partition Asymmetry 0.441176
Average Rall's Ratio 1.61056
Average Bifurcation Angle Local 80.2344 °
Average Bifurcation Angle Remote 68.485 °
Fractal Dimension 1.02361
Complexity Summary
State Equations 149
Optimal Time-Step 0.02330 ms
Relative Complexity 11.52 HH
Model Size
Sections 39
Compartments 121
State Equations 149
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02330 ms
Optimal Time-Step Error 1.11 %
Optimal Time-Step Benchmark Run Time 11.52 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 5.30 %
Max. Stable Time-Step Benchmark Run Time 8.39 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4016 Hz
CVODE Steps Per AP 1614
CVODE Benchmark Run Time 35.58 HH
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