Primary visual area layer 4 spiny 479179020 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Rorb-IRES2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001435
Cell_480051220.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001435
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Delayed Regular Spikers (dRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -86.02 mV
Rheobase Current Interval (0.05150, 0.05356] nA
Threshold Current Interval (0.46875, 0.52734] nA
Bias Current (to -80.00 mV) 0.0212 nA
Testing Temperature 34.0 °C
Stability Interval [-2.1875, 15.0] nA
AP 1-2 Amplitude Drop -0.2211 mV
AP 1 Steady State Amplitude Change 1.6047 mV
AP 1 Amplitude 81.6081 mV
AP 1 Width at Half Height 0.7900 ms
AP 1 Width (Peak To Trough) 7.7600 ms
AP 1 Rate of Change Peak to Trough -13.3377 mV/ms
AP 1 AHP Depth 21.8921 mV
AP2 Amplitude 81.8292 mV
AP2 Width at Half Height 0.7900 ms
AP 2 Width (Peak to Trough) 7.5800 ms
AP 2 Rate of Change Peak to Trough -13.6846 mV/ms
AP 2 AHP Depth 21.8998 mV
AP 1-2 Amplitude Change Percent 0.2709 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change 2.6009 %
AP 1-2 AHP Depth Percent Change 0.0349 %
Input Resistance 282.1240 MΩ
AP 1 Delay Mean 71.7800 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 121.4000 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 50.2200 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -50.0000 %
Steady State Accommodation Mean -50.0000 %
Accommodation Rate to Steady State -0.0601 %/ms
Accommodation at Steady State Mean -74.8284 %
Accommodation Rate Mean at Steady State 410.6252 ms
ISI CV 3.0630
ISI Median 136.0400 ms
ISI Burst Mean Change 2.4184 %
Spike Rate (Strong Stimulation) 35.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 20.8300 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 43.8600 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 23.3400 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2093.7500 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 77.2460 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6253.4 µm2
Number of Stems 10.0
Number of Bifurcations 27.0
Number of Branches 64.0
Overall Width 538.688 µm
Overall Height 241.046 µm
Overall Depth 56.05 µm
Average Diameter 0.347496 µm
Total Length 3308.13 µm
Total Surface 4085.49 µm2
Total Volume 1928.61 µm3
Max Euclidean Distance 473.3 µm
Max Path Distance 515.358 µm
Max Branch Order 8.0
Average Contraction 0.924765
Total Fragmentation 2788.0
Partition Asymmetry 0.437416
Average Rall's Ratio 2.72937
Average Bifurcation Angle Local 58.4368 °
Average Bifurcation Angle Remote 54.6312 °
Fractal Dimension 1.01904
Complexity Summary
State Equations 186
Optimal Time-Step 0.00750 ms
Relative Complexity 28.33 HH
Model Size
Sections 64
Compartments 170
State Equations 186
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00750 ms
Optimal Time-Step Error 0.07 %
Optimal Time-Step Benchmark Run Time 28.33 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 0.40 %
Max. Stable Time-Step Benchmark Run Time 53.12 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 13429 Hz
CVODE Steps Per AP 1121
CVODE Benchmark Run Time 34.44 HH
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