Primary visual area layer 4 spiny 476451456 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Nr5a1-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001434
Cell_477840124.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001434
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -89.49 mV
Rheobase Current Interval (0.06294, 0.06546] nA
Threshold Current Interval (0.58594, 0.64453] nA
Bias Current (to -80.00 mV) 0.0243 nA
Testing Temperature 34.0 °C
Stability Interval [-3.75, 15.0] nA
AP 1-2 Amplitude Drop 15.8122 mV
AP 1 Steady State Amplitude Change 0.3503 mV
AP 1 Amplitude 86.1098 mV
AP 1 Width at Half Height 0.4500 ms
AP 1 Width (Peak To Trough) 4.9700 ms
AP 1 Rate of Change Peak to Trough -17.3461 mV/ms
AP 1 AHP Depth 0.1001 mV
AP2 Amplitude 70.2975 mV
AP2 Width at Half Height 0.4300 ms
AP 2 Width (Peak to Trough) 19.5500 ms
AP 2 Rate of Change Peak to Trough -4.5604 mV/ms
AP 2 AHP Depth 18.8584 mV
AP 1-2 Amplitude Change Percent -18.3629 %
AP 1-2 Half Width Change Percent -4.4444 %
AP 1-2 Rate of Change Peak to Trough Percent Change -73.7093 %
AP 1-2 AHP Depth Percent Change 18740.5887 %
Input Resistance 508.1734 MΩ
AP 1 Delay Mean 73.1100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 79.7900 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 41.9550 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -20.0000 %
Steady State Accommodation Mean -20.0000 %
Accommodation Rate to Steady State -0.0470 %/ms
Accommodation at Steady State Mean -90.3561 %
Accommodation Rate Mean at Steady State 97.2566 ms
ISI CV 4.1456
ISI Median 106.0400 ms
ISI Burst Mean Change 1056.1377 %
Spike Rate (Strong Stimulation) 35.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 20.2700 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 23.3700 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 3.2000 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2131.0900 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 4087.52 µm2
Number of Stems 7.0
Number of Bifurcations 36.0
Number of Branches 79.0
Overall Width 187.074 µm
Overall Height 450.926 µm
Overall Depth 55.56 µm
Average Diameter 0.514251 µm
Total Length 2874.03 µm
Total Surface 4954.48 µm2
Total Volume 1760.99 µm3
Max Euclidean Distance 420.633 µm
Max Path Distance 459.725 µm
Max Branch Order 10.0
Average Contraction 0.902193
Total Fragmentation 2390.0
Partition Asymmetry 0.547354
Average Rall's Ratio 2.14767
Average Bifurcation Angle Local 77.3519 °
Average Bifurcation Angle Remote 66.8997 °
Fractal Dimension 1.03231
Complexity Summary
State Equations 179
Optimal Time-Step 0.03499 ms
Relative Complexity 8.75 HH
Model Size
Sections 77
Compartments 151
State Equations 179
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.03499 ms
Optimal Time-Step Error 2.77 %
Optimal Time-Step Benchmark Run Time 8.75 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 3.34 %
Max. Stable Time-Step Benchmark Run Time 9.56 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 3830 Hz
CVODE Steps Per AP 1477
CVODE Benchmark Run Time 37.44 HH
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