Primary visual area layer 4 spiny 469798159 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Scnn1a-Tg3-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001433
Cell_473872986.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001433
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -96.81 mV
Rheobase Current Interval (0.05653, 0.06088] nA
Threshold Current Interval (1.05469, 1.11328] nA
Bias Current (to -80.00 mV) 0.0266 nA
Testing Temperature 34.0 °C
Stability Interval [-1.25, 15.0] nA
AP 1-2 Amplitude Drop 0.5051 mV
AP 1 Steady State Amplitude Change 0.5443 mV
AP 1 Amplitude 65.2200 mV
AP 1 Width at Half Height 0.3800 ms
AP 1 Width (Peak To Trough) 19.3100 ms
AP 1 Rate of Change Peak to Trough -4.0730 mV/ms
AP 1 AHP Depth 13.4297 mV
AP2 Amplitude 64.7149 mV
AP2 Width at Half Height 0.3800 ms
AP 2 Width (Peak to Trough) 20.5700 ms
AP 2 Rate of Change Peak to Trough -3.9173 mV/ms
AP 2 AHP Depth 15.8632 mV
AP 1-2 Amplitude Change Percent -0.7745 %
AP 1-2 Half Width Change Percent -0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -3.8237 %
AP 1-2 AHP Depth Percent Change 18.1208 %
Input Resistance 934.4916 MΩ
AP 1 Delay Mean 83.9700 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 141.2700 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 66.6950 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -50.0000 %
Steady State Accommodation Mean -25.0000 %
Accommodation Rate to Steady State -0.0338 %/ms
Accommodation at Steady State Mean -66.7253 %
Accommodation Rate Mean at Steady State 258.3631 ms
ISI CV 4.1593
ISI Median 155.8150 ms
ISI Burst Mean Change 32.7923 %
Spike Rate (Strong Stimulation) 36.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 30.7000 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 40.2100 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 18.6600 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2059.1000 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5825.96 µm2
Number of Stems 8.0
Number of Bifurcations 35.0
Number of Branches 78.0
Overall Width 396.941 µm
Overall Height 207.263 µm
Overall Depth 60.34 µm
Average Diameter 0.468081 µm
Total Length 3627.8 µm
Total Surface 5745.95 µm2
Total Volume 2191.24 µm3
Max Euclidean Distance 340.743 µm
Max Path Distance 381.504 µm
Max Branch Order 5.0
Average Contraction 0.870624
Total Fragmentation 2847.0
Partition Asymmetry 0.541224
Average Rall's Ratio 1.91187
Average Bifurcation Angle Local 72.2422 °
Average Bifurcation Angle Remote 61.5807 °
Fractal Dimension 1.04188
Complexity Summary
State Equations 222
Optimal Time-Step 0.02252 ms
Relative Complexity 14.77 HH
Model Size
Sections 74
Compartments 194
State Equations 222
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02252 ms
Optimal Time-Step Error 0.81 %
Optimal Time-Step Benchmark Run Time 14.77 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 2.98 %
Max. Stable Time-Step Benchmark Run Time 10.39 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 3786 Hz
CVODE Steps Per AP 1560
CVODE Benchmark Run Time 42.42 HH
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