Primary visual area layer 4 aspiny 485184849 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Pvalb-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001432
Cell_485694403.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001432
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -88.97 mV
Rheobase Current Interval (0.31036, 0.31311] nA
Threshold Current Interval (0.64453, 0.70312] nA
Bias Current (to -80.00 mV) 0.0760 nA
Testing Temperature 34.0 °C
Stability Interval [-2.5, 15.0] nA
AP 1-2 Amplitude Drop 5.1061 mV
AP 1 Steady State Amplitude Change -11.1116 mV
AP 1 Amplitude 42.5145 mV
AP 1 Width at Half Height 0.2300 ms
AP 1 Width (Peak To Trough) 0.5900 ms
AP 1 Rate of Change Peak to Trough -94.0347 mV/ms
AP 1 AHP Depth 12.9660 mV
AP2 Amplitude 37.4085 mV
AP2 Width at Half Height 0.2600 ms
AP 2 Width (Peak to Trough) 8.4700 ms
AP 2 Rate of Change Peak to Trough -6.1970 mV/ms
AP 2 AHP Depth 15.0805 mV
AP 1-2 Amplitude Change Percent -12.0102 %
AP 1-2 Half Width Change Percent 13.0435 %
AP 1-2 Rate of Change Peak to Trough Percent Change -93.4098 %
AP 1-2 AHP Depth Percent Change 16.3087 %
Input Resistance 111.1385 MΩ
AP 1 Delay Mean 14.8500 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 22.6000 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 14.6150 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 15.6250 %
Steady State Accommodation Mean 18.7500 %
Accommodation Rate to Steady State 0.4254 %/ms
Accommodation at Steady State Mean -30.4446 %
Accommodation Rate Mean at Steady State 0.1125 ms
ISI CV 11.0360
ISI Median 10.8600 ms
ISI Burst Mean Change 177.1613 %
Spike Rate (Strong Stimulation) 10.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 1.5500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 3.2600 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 9.7300 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2012.1400 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 7572.09 µm2
Number of Stems 7.0
Number of Bifurcations 22.0
Number of Branches 51.0
Overall Width 168.539 µm
Overall Height 308.094 µm
Overall Depth 48.03 µm
Average Diameter 0.555174 µm
Total Length 2531.2 µm
Total Surface 4916.01 µm2
Total Volume 2614.35 µm3
Max Euclidean Distance 213.071 µm
Max Path Distance 234.912 µm
Max Branch Order 5.0
Average Contraction 0.939863
Total Fragmentation 2071.0
Partition Asymmetry 0.256061
Average Rall's Ratio 2.59731
Average Bifurcation Angle Local 63.7324 °
Average Bifurcation Angle Remote 54.1005 °
Fractal Dimension 1.01675
Complexity Summary
State Equations 163
Optimal Time-Step 0.02446 ms
Relative Complexity 11.31 HH
Model Size
Sections 51
Compartments 135
State Equations 163
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02446 ms
Optimal Time-Step Error 1.95 %
Optimal Time-Step Benchmark Run Time 11.31 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 5.99 %
Max. Stable Time-Step Benchmark Run Time 8.64 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 13179 Hz
CVODE Steps Per AP 1200
CVODE Benchmark Run Time 45.79 HH
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