Primary visual area layer 4 spiny 478586295 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Rorb-IRES2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001431
Cell_479427516.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001431
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Bursters (B)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -71.19 mV
Rheobase Current Interval (0.15450, 0.15656] nA
Threshold Current Interval (0.46875, 0.52734] nA
Bias Current (to -80.00 mV) -0.1334 nA
Testing Temperature 34.0 °C
Stability Interval [-2.1875, 15.0] nA
AP 1-2 Amplitude Drop 1.2019 mV
AP 1 Steady State Amplitude Change 10.0749 mV
AP 1 Amplitude 63.5872 mV
AP 1 Width at Half Height 0.8700 ms
AP 1 Width (Peak To Trough) 4.0700 ms
AP 1 Rate of Change Peak to Trough -19.7400 mV/ms
AP 1 AHP Depth 16.7547 mV
AP2 Amplitude 62.3852 mV
AP2 Width at Half Height 0.8800 ms
AP 2 Width (Peak to Trough) 4.2000 ms
AP 2 Rate of Change Peak to Trough -18.7482 mV/ms
AP 2 AHP Depth 16.3573 mV
AP 1-2 Amplitude Change Percent -1.8902 %
AP 1-2 Half Width Change Percent 1.1494 %
AP 1-2 Rate of Change Peak to Trough Percent Change -5.0243 %
AP 1-2 AHP Depth Percent Change -2.3719 %
Input Resistance 66.9117 MΩ
AP 1 Delay Mean 11.5200 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 26.8500 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 15.6000 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -62.5000 %
Steady State Accommodation Mean -75.0000 %
Accommodation Rate to Steady State -0.1579 %/ms
Accommodation at Steady State Mean -105.5466 %
Accommodation Rate Mean at Steady State 208.6584 ms
ISI CV 1.5563
ISI Median 171.1150 ms
ISI Burst Mean Change 3.5225 %
Spike Rate (Strong Stimulation) 17.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 3.2100 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 12.3200 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 9.0450 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2087.9600 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 71.3896 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6237.51 µm2
Number of Stems 11.0
Number of Bifurcations 17.0
Number of Branches 45.0
Overall Width 201.232 µm
Overall Height 662.888 µm
Overall Depth 44.01 µm
Average Diameter 0.650919 µm
Total Length 2902.76 µm
Total Surface 6299.27 µm2
Total Volume 2633.9 µm3
Max Euclidean Distance 567.705 µm
Max Path Distance 680.772 µm
Max Branch Order 10.0
Average Contraction 0.87907
Total Fragmentation 2454.0
Partition Asymmetry 0.51634
Average Rall's Ratio 2.35208
Average Bifurcation Angle Local 80.8264 °
Average Bifurcation Angle Remote 70.0495 °
Fractal Dimension 1.0333
Complexity Summary
State Equations 157
Optimal Time-Step 0.01074 ms
Relative Complexity 15.90 HH
Model Size
Sections 45
Compartments 141
State Equations 157
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01074 ms
Optimal Time-Step Error 1.01 %
Optimal Time-Step Benchmark Run Time 15.90 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 4.33 %
Max. Stable Time-Step Benchmark Run Time 21.35 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 9331 Hz
CVODE Steps Per AP 1368
CVODE Benchmark Run Time 25.85 HH
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