Primary visual area layer 6a spiny 466632464 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 6a
Keywords: Mus musculus, Ntsr1-Cre_GN220
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001430
Cell_480631402.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001430
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -88.22 mV
Rheobase Current Interval (0.09888, 0.10300] nA
Threshold Current Interval (0.99609, 1.05469] nA
Bias Current (to -80.00 mV) 0.0250 nA
Testing Temperature 34.0 °C
Stability Interval [-3.4375, 15.0] nA
AP 1-2 Amplitude Drop 0.7633 mV
AP 1 Steady State Amplitude Change 1.9702 mV
AP 1 Amplitude 55.8225 mV
AP 1 Width at Half Height 1.0600 ms
AP 1 Width (Peak To Trough) 7.5000 ms
AP 1 Rate of Change Peak to Trough -9.1442 mV/ms
AP 1 AHP Depth 12.7590 mV
AP2 Amplitude 55.0592 mV
AP2 Width at Half Height 1.0900 ms
AP 2 Width (Peak to Trough) 8.3100 ms
AP 2 Rate of Change Peak to Trough -8.5432 mV/ms
AP 2 AHP Depth 15.9346 mV
AP 1-2 Amplitude Change Percent -1.3673 %
AP 1-2 Half Width Change Percent 2.8302 %
AP 1-2 Rate of Change Peak to Trough Percent Change -6.5727 %
AP 1-2 AHP Depth Percent Change 24.8889 %
Input Resistance 359.7266 MΩ
AP 1 Delay Mean 53.2300 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 86.1400 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 63.5000 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -25.0000 %
Steady State Accommodation Mean -25.0000 %
Accommodation Rate to Steady State -0.0743 %/ms
Accommodation at Steady State Mean -77.2999 %
Accommodation Rate Mean at Steady State 78.7925 ms
ISI CV 4.4934
ISI Median 131.8900 ms
ISI Burst Mean Change 185.9009 %
Spike Rate (Strong Stimulation) 12.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 16.5700 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 154.7400 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 116.0100 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2085.7200 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 129.8409 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5840.57 µm2
Number of Stems 8.0
Number of Bifurcations 29.0
Number of Branches 66.0
Overall Width 199.141 µm
Overall Height 658.224 µm
Overall Depth 52.85 µm
Average Diameter 0.72871 µm
Total Length 3664.19 µm
Total Surface 8785.95 µm2
Total Volume 3224.51 µm3
Max Euclidean Distance 729.96 µm
Max Path Distance 814.668 µm
Max Branch Order 18.0
Average Contraction 0.883349
Total Fragmentation 3150.0
Partition Asymmetry 0.716024
Average Rall's Ratio 2.66808
Average Bifurcation Angle Local 83.7101 °
Average Bifurcation Angle Remote 92.4065 °
Fractal Dimension 1.037
Complexity Summary
State Equations 212
Optimal Time-Step 0.01084 ms
Relative Complexity 20.23 HH
Model Size
Sections 66
Compartments 196
State Equations 212
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01084 ms
Optimal Time-Step Error 0.19 %
Optimal Time-Step Benchmark Run Time 20.23 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 2.21 %
Max. Stable Time-Step Benchmark Run Time 27.39 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 11186 Hz
CVODE Steps Per AP 1377
CVODE Benchmark Run Time 35.96 HH
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