Izhikevich Integrator Cell

Model Type:
Cell
Neurolex IDs: None
Keywords: , Neuron or other electrically excitable cell, Action Potential Initiation, Activity Patterns, Parameter Fitting, Simplified Models, Tutorial/Teaching, Action Potentials
Publication: Izhikevich (2003) Simple model of spiking neurons
Authors:
EM Izhikevich  
Translators: Padraig Gleeson   Andrew Davison   Vitor Chaud  
Sources:
Files:
Model ID NeuroML File
NMLCL001418
IzhikevichIntegrator.cell.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001418
Associated Channels: None
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -60.00 mV
Rheobase Current Interval (2.27234, 2.30347] nA
Threshold Current Interval (7.91016, 7.96875] nA
Bias Current (to -80.00 mV) -10.0001 nA
Testing Temperature 36.0 °C
Stability Interval [-10.0, 15.0] nA
AP 1-2 Amplitude Drop -1.2460 mV
AP 1 Steady State Amplitude Change -0.6033 mV
AP 1 Amplitude 63.7010 mV
AP 1 Width at Half Height 0.2100 ms
AP 1 Width (Peak To Trough) 5.0200 ms
AP 1 Rate of Change Peak to Trough -18.3466 mV/ms
AP 1 AHP Depth 28.3991 mV
AP2 Amplitude 64.9470 mV
AP2 Width at Half Height 0.2000 ms
AP 2 Width (Peak to Trough) 4.6900 ms
AP 2 Rate of Change Peak to Trough -19.6711 mV/ms
AP 2 AHP Depth 27.3106 mV
AP 1-2 Amplitude Change Percent 1.9560 %
AP 1-2 Half Width Change Percent -4.7619 %
AP 1-2 Rate of Change Peak to Trough Percent Change 7.2193 %
AP 1-2 AHP Depth Percent Change -3.8329 %
Input Resistance 1.4620 MΩ
AP 1 Delay Mean 18.2600 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 145.4400 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 128.0000 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -1.1805 %
Accommodation Rate Mean at Steady State 5.2454 ms
ISI CV 332.1095
ISI Median 128.6800 ms
ISI Burst Mean Change 1.2895 %
Spike Rate (Strong Stimulation) 19.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 4.3400 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 38.7800 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 43.7950 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2082.0700 ms
Frequency Filter Type Constant
Single compartment, abstract, or point cells do not have morphology data.
Complexity Summary
Relative Complexity 0.46 HH
State Equations 2
Optimal Time-Step 0.03205 ms
Model Size
Sections 1
Compartments 1
State Equations 2
Variable Time-Step Complexity
CVODE Steady State Step Frequency 379 Hz
CVODE Steps Per AP 1016
CVODE Benchmark Run Time 0.46 HH
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