Izhikevich Bistable Cell

Model Type:
Cell
Neurolex IDs: None
Keywords: , Neuron or other electrically excitable cell, Action Potential Initiation, Activity Patterns, Parameter Fitting, Simplified Models, Tutorial/Teaching, Action Potentials
Publication: Izhikevich (2003) Simple model of spiking neurons
Authors:
EM Izhikevich  
Translators: Padraig Gleeson   Andrew Davison   Vitor Chaud  
Sources:
Files:
Model ID NeuroML File
NMLCL001414
IzhikevichBistable.cell.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001414
Associated Channels: None
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -62.50 mV
Rheobase Current Interval (0.20599, 0.20943] nA
Threshold Current Interval (0.82031, 0.87891] nA
Bias Current (to -80.00 mV) -7.0667 nA
Testing Temperature 36.0 °C
Stability Interval [-10.0, 15.0] nA
AP 1-2 Amplitude Drop 1.1138 mV
AP 1 Steady State Amplitude Change 2.1710 mV
AP 1 Amplitude 76.5172 mV
AP 1 Width at Half Height 0.1800 ms
AP 1 Width (Peak To Trough) 6.7900 ms
AP 1 Rate of Change Peak to Trough -14.4455 mV/ms
AP 1 AHP Depth 21.5679 mV
AP2 Amplitude 75.4034 mV
AP2 Width at Half Height 0.1900 ms
AP 2 Width (Peak to Trough) 6.9400 ms
AP 2 Rate of Change Peak to Trough -13.8684 mV/ms
AP 2 AHP Depth 20.8435 mV
AP 1-2 Amplitude Change Percent -1.4556 %
AP 1-2 Half Width Change Percent 5.5556 %
AP 1-2 Rate of Change Peak to Trough Percent Change -3.9950 %
AP 1-2 AHP Depth Percent Change -3.3589 %
Input Resistance 3.6043 MΩ
AP 1 Delay Mean 16.6300 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 51.6400 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 35.1050 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -0.1820 %
Accommodation Rate Mean at Steady State 0.7123 ms
ISI CV 399.6448
ISI Median 35.0500 ms
ISI Burst Mean Change 0.5427 %
Spike Rate (Strong Stimulation) 36.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 9.5000 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 37.2400 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 27.7050 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2991.6100 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 45.0164 Hz
Single compartment, abstract, or point cells do not have morphology data.
Complexity Summary
Relative Complexity 0.36 HH
State Equations 2
Optimal Time-Step 0.03120 ms
Model Size
Sections 1
Compartments 1
State Equations 2
Variable Time-Step Complexity
CVODE Steady State Step Frequency -59 Hz
CVODE Steps Per AP 754
CVODE Benchmark Run Time 0.36 HH
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