Izhikevich Spike Frequency Adapting Cell

Model Type:
Cell
Neurolex IDs: None
Keywords: , Neuron or other electrically excitable cell, Action Potential Initiation, Activity Patterns, Parameter Fitting, Simplified Models, Tutorial/Teaching, Action Potentials
Publication: Izhikevich (2003) Simple model of spiking neurons
Authors:
EM Izhikevich  
Translators: Padraig Gleeson   Andrew Davison   Vitor Chaud  
Sources:
Files:
Model ID NeuroML File
NMLCL001408
IzhikevichSpikeFrequencyAdapting.cell.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001408
Associated Channels: None
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -70.00 mV
Rheobase Current Interval (2.55707, 2.58316] nA
Threshold Current Interval (6.62109, 6.67969] nA
Bias Current (to -80.00 mV) -4.9974 nA
Testing Temperature 36.0 °C
Stability Interval [-10.0, 15.0] nA
AP 1-2 Amplitude Drop -0.1455 mV
AP 1 Steady State Amplitude Change 0.3673 mV
AP 1 Amplitude 75.6127 mV
AP 1 Width at Half Height 0.1900 ms
AP 1 Width (Peak To Trough) 5.2600 ms
AP 1 Rate of Change Peak to Trough -20.0132 mV/ms
AP 1 AHP Depth 29.6568 mV
AP2 Amplitude 75.7583 mV
AP2 Width at Half Height 0.1900 ms
AP 2 Width (Peak to Trough) 4.8200 ms
AP 2 Rate of Change Peak to Trough -22.2355 mV/ms
AP 2 AHP Depth 31.4167 mV
AP 1-2 Amplitude Change Percent 0.1924 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change 11.1039 %
AP 1-2 AHP Depth Percent Change 5.9342 %
Input Resistance 1.1459 MΩ
AP 1 Delay Mean 8.3100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 273.7300 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 272.8450 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -5.3080 %
Accommodation Rate Mean at Steady State 10.0000 ms
ISI CV 53.4286
ISI Median 280.3000 ms
ISI Burst Mean Change 5.5949 %
Spike Rate (Strong Stimulation) 10.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 3.0900 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 65.6000 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 83.9950 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2423.4100 ms
Frequency Filter Type Constant
Single compartment, abstract, or point cells do not have morphology data.
Complexity Summary
Relative Complexity 0.38 HH
State Equations 2
Optimal Time-Step 0.03178 ms
Model Size
Sections 1
Compartments 1
State Equations 2
Variable Time-Step Complexity
CVODE Steady State Step Frequency 1784 Hz
CVODE Steps Per AP 694
CVODE Benchmark Run Time 0.38 HH
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