Superficial Layer 2/3 Fast Rhythmic Bursting (FRB) Pyramidal Cell

Model Type:
Neurolex IDs: Neocortex pyramidal layer 2-3 cell,corticocortical cell, superficial pyramidal cell, Neocortex pyramidal neuron layer 2-3, Layer 2-3 pyramidal cell, Neocortical pyramidal neuron: superficial, deep layer (layer 5, 6) pyramidal cell
Keywords: muticompartment,soma,dendrites,axon,kainate,persistent gamma oscillations,thalamocortical sleep spindles,synchronized population bursts,electrographic seizures,isolated double population bursts with superimposed very fast oscillations,spike-wave,polyspike-wave,fast runs,epileptiform bursts,Electrical coupling, Realistic Network, Activity Patterns, Bursting, Temporal Pattern Generation, Oscillations, Simplified Models, Epilepsy, Sleep, Spindles
Publication: Traub, et. al. (2005) Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts
RD Traub   D Contreras   MO Cunningham   H Murray   FE LeBeau   A Roopun   A Bibbig   WB Wilent   MJ Higley   MA Whittington  
Translators: Padraig Gleeson   Eugenio Piasini   Chaitanya Chintaluri   Daniel Wojcik   Helena Glabska   Jacek Rogala   Michael Hines   Subhasis Ray   Tom├ís Alfonso   Yates Buckley  
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Notes: None
Model Id: NMLCL001137
Associated Channels:
Associated Synapses: None
Associated Networks:
Current Clamp Response
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Non-Positive Rheobase (npRB)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking Yes
Resting Voltage N/A mV
Rheobase Current Interval (N/A, N/A] nA
Threshold Current Interval (N/A, N/A] nA
Bias Current (to N/A mV) N/A nA
Testing Temperature 6.3 °C
Stability Interval [-10.0, 15.0] nA
AP 1-2 Amplitude Drop N/A mV
AP 1 Steady State Amplitude Change N/A mV
AP 1 Amplitude N/A mV
AP 1 Width at Half Height N/A ms
AP 1 Width (Peak To Trough) N/A ms
AP 1 Rate of Change Peak to Trough N/A mV/ms
AP 1 AHP Depth N/A mV
AP2 Amplitude N/A mV
AP2 Width at Half Height N/A ms
AP 2 Width (Peak to Trough) N/A ms
AP 2 Rate of Change Peak to Trough N/A mV/ms
AP 2 AHP Depth N/A mV
AP 1-2 Amplitude Change Percent N/A %
AP 1-2 Half Width Change Percent N/A %
AP 1-2 Rate of Change Peak to Trough Percent Change N/A %
AP 1-2 AHP Depth Percent Change N/A %
Input Resistance N/A MΩ
AP 1 Delay Mean N/A ms
AP 1 Delay SD N/A ms
AP 2 Delay Mean N/A ms
AP 2 Delay SD N/A ms
Burst 1 ISI Mean N/A ms
Burst 1 ISI SD N/A ms
Initial Accommodation Mean N/A %
Steady State Accommodation Mean N/A %
Accommodation Rate to Steady State N/A %/ms
Accommodation at Steady State Mean N/A %
Accommodation Rate Mean at Steady State N/A ms
ISI Median N/A ms
ISI Burst Mean Change N/A %
Spike Rate (Strong Stimulation) N/A Hz
AP 1 Delay Mean (Strong Stimulation) N/A ms
AP 1 Delay SD (Strong Stimulation) N/A ms
AP 2 Delay Mean (Strong Stimulation) N/A ms
AP 2 Delay SD (Strong Stimulation) N/A ms
Burst 1 ISI Mean (Strong Stimulation) N/A ms
Burst 1 ISI SD (Strong Stimulation) N/A ms
Ramp First Spike Time N/A ms
Frequency Filter Type N/A
Frequency Filter Pass Above N/A Hz
Frequency Filter Pass Below N/A Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 0.0 µm2
Number of Stems 0.0
Number of Bifurcations 21.0
Number of Branches 43.0
Overall Width 253.834 µm
Overall Height 528.805 µm
Overall Depth 228.92 µm
Average Diameter 1.92651 µm
Total Length 3667.89 µm
Total Surface 19285.5 µm2
Total Volume 15140.4 µm3
Max Euclidean Distance 408.965 µm
Max Path Distance 435.7 µm
Max Branch Order 9.0
Average Contraction 0.989567
Total Fragmentation 166.0
Partition Asymmetry 0.643915
Average Rall's Ratio 1.0975
Average Bifurcation Angle Local 96.6322 °
Average Bifurcation Angle Remote 79.0767 °
Fractal Dimension 1.00076
Complexity Summary
Relative Complexity N/A HH
State Equations 11468
Optimal Time-Step N/A ms
Model Size
Sections 74
Compartments 763
State Equations 11468
Variable Time-Step Complexity
CVODE Steady State Step Frequency N/A Hz
CVODE Steps Per AP N/A
CVODE Benchmark Run Time N/A HH
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