Main Olfactory Bulb Mitral Cell (5)

Model Type:
Cell
Neurolex IDs: Olfactory bulb (main) mitral cell
Keywords: main olfactory bulb, glutamate
Publication: Migliore, et. al. (2014) Distributed organization of a brain microcircuit analyzed by three-dimensional modeling: the olfactory bulb.
Authors:
Michele Migliore   Francesco Cavarretta   Michael Hines   Gordon Shepherd  
Translators: Justas Birgiolas   Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL001133
Mitral_0_4.cell.nml
( view NeuroML )
NMLCH000134
kamt.channel.nml
( view NeuroML )
NMLCH000135
kdrmt.channel.nml
( view NeuroML )
NMLCH000136
nax__sh0.channel.nml
( view NeuroML )
NMLCH000137
nax__sh10.channel.nml
( view NeuroML )
NMLCH000139
pas.channel.nml
( view NeuroML )
Current Clamp Response:
Instructions
Protocol:
Meta Protocol: -
Stimulus: -

Protocols

The dropdown contains the list of protocols to which the model was subjected. Select one from the drop down to see the model's response.

Stimuli

Some protocols have multiple stimuli (e.g. voltage levels held or current amplitudes injected). If so, a "Stimulus" slider will be visible when a protocol with multiple stimuli is selected. When visible, drag the slider left/right to see the model's response to a specific protocol stimulus. By default, the traces of all protocol stimuli are shown superimposed, each trace indicated by a different color.

Meta-Protocols

Some models will have additional meta-protocol parameters (e.g. different calcium concentration levels, random noise seeds). If available, use the second slider to see the effect of changing the meta-protocol parameter on the model response. When both sliders are visible, their values can be changed independently.

Trace detail

Using the mouse, hover near a point on a trace to see a popup with the point details. Top value shows the time. The bottom left value shows the name of the protocol stimulus, and the bottom right value shows the value of the plotted variable (e.g. voltage or current)

Zoom

The plots can be zoomed in/out to see plot details. On the right side of the plot, use the [+] and [-] buttons to zoom in/out on the center of the plot.

Pan

Once zoomed, the plots can be panned by dragging the mouse or swiping fingers sideways.

Reset Plot

Once a zoom/pan position is set, it will be maintained when the stimulus/meta-protocol parameter is changed. To reset the zoom/pan, click the circular arrow button below the zoom out button. Plot zoom will also be reset when the protocol is changed.

Morphology:
Cell Properties:
Membrane Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -67.24 mV
Rheobase Current Interval (0.6056, 0.6104] nA
Threshold Current Interval (1.1719, 1.2305] nA
Bias Current (to -80.00 mV) -0.7758 nA
Testing Temperature 35.0 °C
Complexity Properties
Sections 44
Compartments 660
State Equations 3960
Stability Interval [-5.625, 15.0] nA
 
Maximum Stable dt 0.03125 ms
Maximum Stable dt Error 1.04 %
Max. Stable dt Benchmark Run time 6992.94 HH
 
Run time-vs-Error Optimal dt 0.00543 ms
Optimal dt Error 0.12 %
Optimal dt Benchmark Run time 2574.38 HH
 
CVODE Steady State Step Frequency 17368 Hz
CVODE Steps Per AP 705
CVODE Benchmark Run time 2245.75 HH
Associated Channels:
Associated Synapses: None
Associated Networks: None
Notes: None
Model Id: NMLCL001133
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