Main Olfactory Bulb Mitral Cell (2)

Model Type:
Cell
Neurolex IDs: Olfactory bulb (main) mitral cell
Keywords: main olfactory bulb, glutamate
Publication: Migliore, et. al. (2014) Distributed organization of a brain microcircuit analyzed by three-dimensional modeling: the olfactory bulb.
Authors:
Michele Migliore   Francesco Cavarretta   Michael Hines   Gordon Shepherd  
Translators: Justas Birgiolas   Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL001130
Mitral_0_1.cell.nml
( view NeuroML )
NMLCH000134
kamt.channel.nml
( view NeuroML )
NMLCH000135
kdrmt.channel.nml
( view NeuroML )
NMLCH000136
nax__sh0.channel.nml
( view NeuroML )
NMLCH000137
nax__sh10.channel.nml
( view NeuroML )
NMLCH000139
pas.channel.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001130
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -67.27 mV
Rheobase Current Interval (0.46875, 0.47241] nA
Threshold Current Interval (0.87891, 0.93750] nA
Bias Current (to -80.00 mV) -0.6082 nA
Testing Temperature 35.0 °C
Stability Interval [-4.375, 15.0] nA
AP 1-2 Amplitude Drop 0.8440 mV
AP 1 Steady State Amplitude Change 1.1081 mV
AP 1 Amplitude 95.9094 mV
AP 1 Width at Half Height 1.4100 ms
AP 1 Width (Peak To Trough) 3.4900 ms
AP 1 Rate of Change Peak to Trough -34.5540 mV/ms
AP 1 AHP Depth 24.6839 mV
AP2 Amplitude 95.0655 mV
AP2 Width at Half Height 1.4000 ms
AP 2 Width (Peak to Trough) 3.5300 ms
AP 2 Rate of Change Peak to Trough -34.0458 mV/ms
AP 2 AHP Depth 25.1161 mV
AP 1-2 Amplitude Change Percent -0.8800 %
AP 1-2 Half Width Change Percent -0.7092 %
AP 1-2 Rate of Change Peak to Trough Percent Change -1.4708 %
AP 1-2 AHP Depth Percent Change 1.7507 %
Input Resistance 19.4953 MΩ
AP 1 Delay Mean 5.5400 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 72.6400 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 69.7050 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -16.6667 %
Steady State Accommodation Mean -16.6667 %
Accommodation Rate to Steady State -0.1150 %/ms
Accommodation at Steady State Mean -7.2313 %
Accommodation Rate Mean at Steady State 13.0372 ms
ISI CV 73.0351
ISI Median 72.3300 ms
ISI Burst Mean Change 7.7645 %
Spike Rate (Strong Stimulation) 40.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 1.3800 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 13.9100 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 17.0100 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2020.3200 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 14744.5 µm2
Number of Stems 6.0
Number of Bifurcations 15.0
Number of Branches 34.0
Overall Width 1195.43 µm
Overall Height 1618.8 µm
Overall Depth 738.53 µm
Average Diameter 2.71858 µm
Total Length 9804.39 µm
Total Surface 71541.0 µm2
Total Volume 49063.1 µm3
Max Euclidean Distance 974.213 µm
Max Path Distance 1193.8 µm
Max Branch Order 5.0
Average Contraction 0.932708
Total Fragmentation 520.0
Partition Asymmetry 0.558333
Average Rall's Ratio 1.4725
Average Bifurcation Angle Local 65.1447 °
Average Bifurcation Angle Remote 58.4107 °
Fractal Dimension 1.01122
Complexity Summary
State Equations 2958
Optimal Time-Step 0.00543 ms
Relative Complexity 1728.66 HH
Model Size
Sections 30
Compartments 493
State Equations 2958
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00543 ms
Optimal Time-Step Error 0.16 %
Optimal Time-Step Benchmark Run Time 1728.66 HH
 
Maximum Stable Time-Step 0.03125 ms
Maximum Stable Time-Step Error 0.81 %
Max. Stable Time-Step Benchmark Run Time 4688.02 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 16781 Hz
CVODE Steps Per AP 712
CVODE Benchmark Run Time 1474.03 HH
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