Layer 6 Delayed Stuttering Nest Basket Cell (5)

Model Type:
Cell
Neurolex IDs: Neocortex basket cell
Neocortex Layer 6
Keywords: delayed stuttering,Layer 6,Fast-spiking, interneuron, GABAergic, inhibitory, neocortex, rat, somatosensory cortex, nest, basket, biophysical, delayed stuttering nest basket cell, Realistic Network, Neuron or other electrically excitable cell, Synapse, Spatio-temporal Activity Patterns, Detailed Neuronal Models
Publication: Markram, et. al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry.
Authors:
H Markram   Eilif Muller   Srikanth Ramaswamy   Michael Reimann   Marwan Abdellah   Carlos Sanchez   Anastasia Ailamaki   Lidia Alonso-Nanclares   Nicolas Antille   Selim Arsever   Guy Kahou   Thomas Berger   Ahmet Bilgili   Nenad Buncic   Athanassia Chalimourda   Giuseppe Chindemi   Jean-Denis Courcol   Fabien Delalondre   Vincent Delattre   Shaul Druckmann   Raphael Dumusc   James Dynes   Stefan Eilemann   Eyal Gal   Michael Gevaert   Jean-Pierre Ghobril   Albert Gidon   Joe Graham   Anirudh Gupta   Valentin Haenel   E Hay   Thomas Heinis   Juan Hernando   Michael Hines   Lida Kanari   Daniel Keller   John Kenyon   Georges Khazen   Yihwa Kim   James King   Zoltan Kisvarday   Pramod Kumbhar   Jean-Vincent Le Bé   Bruno Magalhães   Angel Merchán-Pérez   Julie Meystre   Benjamin Morrice   Jeffrey Muller   Alberto Muñoz-Céspedes   Shruti Muralidhar   Keerthan Muthurasa   Daniel Nachbaur   Taylor Newton   Max Nolte   Aleksandr Ovcharenko   Juan Palacios   Luis Pastor   Rodrigo Perin   Rajnish Ranjan   Imad Riachi   Juan Riquelme   Christian Rössert   Konstantinos Sfyrakis   Ying Shi   Julian Shillcock   Gilad Silberberg   Ricardo Silva   Farhan Tauheed   Martin Telefont   Maria Toledo-Rodriguez   Thomas Tränkler   Werner Van Geit   Jafet Diaz   Richard Walker   Yun Wang   Stefano Zaninetta   Javier DeFelipe   S Hill   Idan Segev   F Schürmann  
Translators: Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL001121
dSTUT214_L6_NBC_750f7ba17d_0_0.cell.nml
( view NeuroML )
NMLCH000101
Ca.channel.nml
( view NeuroML )
NMLCH000103
Ca_LVAst.channel.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000105
Im.channel.nml
( view NeuroML )
NMLCH000106
KdShu2007.channel.nml
( view NeuroML )
NMLCH000107
K_Pst.channel.nml
( view NeuroML )
NMLCH000108
K_Tst.channel.nml
( view NeuroML )
NMLCH000109
Nap_Et2.channel.nml
( view NeuroML )
NMLCH000110
NaTa_t.channel.nml
( view NeuroML )
NMLCH000111
NaTs2_t.channel.nml
( view NeuroML )
NMLCH000112
SK_E2.channel.nml
( view NeuroML )
NMLCH000113
SKv3_1.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCH000115
StochKv_deterministic.channel.nml
( view NeuroML )
NMLCN000001
CaDynamics_E2_NML2.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001121
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -75.16 mV
Rheobase Current Interval (0.18265, 0.18402] nA
Threshold Current Interval (0.29297, 0.35156] nA
Bias Current (to -70.00 mV) 0.0333 nA
Testing Temperature 34.0 °C
Stability Interval [-1.5625, 15.0] nA
AP 1-2 Amplitude Drop 6.3676 mV
AP 1 Steady State Amplitude Change 6.6387 mV
AP 1 Amplitude 81.3332 mV
AP 1 Width at Half Height 0.5500 ms
AP 1 Width (Peak To Trough) 2.3700 ms
AP 1 Rate of Change Peak to Trough -43.0528 mV/ms
AP 1 AHP Depth 20.7019 mV
AP2 Amplitude 74.9655 mV
AP2 Width at Half Height 0.5500 ms
AP 2 Width (Peak to Trough) 2.2900 ms
AP 2 Rate of Change Peak to Trough -41.9992 mV/ms
AP 2 AHP Depth 21.2126 mV
AP 1-2 Amplitude Change Percent -7.8291 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -2.4471 %
AP 1-2 AHP Depth Percent Change 2.4672 %
Input Resistance 204.3810 MΩ
AP 1 Delay Mean 4.7300 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 23.3100 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 19.5450 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -6.2663 %
Accommodation Rate Mean at Steady State 0.0121 ms
ISI CV 85.8884
ISI Median 19.8100 ms
ISI Burst Mean Change 10.3875 %
Spike Rate (Strong Stimulation) 89.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 1.6500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 10.9700 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 10.2500 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2101.8300 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 78.3275 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 9113.12 µm2
Number of Stems 5.0
Number of Bifurcations 29.0
Number of Branches 62.0
Overall Width 418.918 µm
Overall Height 787.76 µm
Overall Depth 307.5 µm
Average Diameter 0.681802 µm
Total Length 5538.61 µm
Total Surface 8346.51 µm2
Total Volume 3853.79 µm3
Max Euclidean Distance 571.177 µm
Max Path Distance 601.139 µm
Max Branch Order 7.0
Average Contraction 0.980417
Total Fragmentation 1184.0
Partition Asymmetry 0.580172
Average Rall's Ratio 1.11167
Average Bifurcation Angle Local 35.071 °
Average Bifurcation Angle Remote 48.4001 °
Fractal Dimension 1.00255
Complexity Summary
Relative Complexity 1033.53 HH
State Equations 3642
Optimal Time-Step 0.00775 ms
Model Size
Sections 63
Compartments 279
State Equations 3642
Variable Time-Step Complexity
CVODE Steady State Step Frequency 19065 Hz
CVODE Steps Per AP 210
CVODE Benchmark Run Time 1033.53 HH
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