Layer 4 Delayed Non-accommodating Small Basket Cell (5)

Model Type:
Cell
Neurolex IDs: Neocortex basket cell
Neocortex Layer 4
Keywords: delayed non-accommodating,Layer 4,Fast-spiking, interneuron, GABAergic, inhibitory, neocortex, rat, somatosensory cortex, small, basket
Publication: Markram, et. al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry.
Authors:
H Markram   Eilif Muller   Srikanth Ramaswamy   Michael Reimann   Marwan Abdellah   Carlos Sanchez   Anastasia Ailamaki   Lidia Alonso-Nanclares   Nicolas Antille   Selim Arsever   Guy Kahou   Thomas Berger   Ahmet Bilgili   Nenad Buncic   Athanassia Chalimourda   Giuseppe Chindemi   Jean-Denis Courcol   Fabien Delalondre   Vincent Delattre   Shaul Druckmann   Raphael Dumusc   James Dynes   Stefan Eilemann   Eyal Gal   Michael Gevaert   Jean-Pierre Ghobril   Albert Gidon   Joe Graham   Anirudh Gupta   Valentin Haenel   E Hay   Thomas Heinis   Juan Hernando   Michael Hines   Lida Kanari   Daniel Keller   John Kenyon   Georges Khazen   Yihwa Kim   James King   Zoltan Kisvarday   Pramod Kumbhar   Jean-Vincent Le Bé   Bruno Magalhães   Angel Merchán-Pérez   Julie Meystre   Benjamin Morrice   Jeffrey Muller   Alberto Muñoz-Céspedes   Shruti Muralidhar   Keerthan Muthurasa   Daniel Nachbaur   Taylor Newton   Max Nolte   Aleksandr Ovcharenko   Juan Palacios   Luis Pastor   Rodrigo Perin   Rajnish Ranjan   Imad Riachi   Juan Riquelme   Christian Rössert   Konstantinos Sfyrakis   Ying Shi   Julian Shillcock   Gilad Silberberg   Ricardo Silva   Farhan Tauheed   Martin Telefont   Maria Toledo-Rodriguez   Thomas Tränkler   Werner Van Geit   Jafet Diaz   Richard Walker   Yun Wang   Stefano Zaninetta   Javier DeFelipe   S Hill   Idan Segev   F Schürmann  
Translators: Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL001051
dNAC222_L4_SBC_f48f4f7670_0_0.cell.nml
( view NeuroML )
NMLCH000101
Ca.channel.nml
( view NeuroML )
NMLCH000103
Ca_LVAst.channel.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000105
Im.channel.nml
( view NeuroML )
NMLCH000106
KdShu2007.channel.nml
( view NeuroML )
NMLCH000107
K_Pst.channel.nml
( view NeuroML )
NMLCH000108
K_Tst.channel.nml
( view NeuroML )
NMLCH000109
Nap_Et2.channel.nml
( view NeuroML )
NMLCH000110
NaTa_t.channel.nml
( view NeuroML )
NMLCH000111
NaTs2_t.channel.nml
( view NeuroML )
NMLCH000112
SK_E2.channel.nml
( view NeuroML )
NMLCH000113
SKv3_1.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCN000001
CaDynamics_E2_NML2.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001051
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -71.67 mV
Rheobase Current Interval (0.04669, 0.04761] nA
Threshold Current Interval (0.17578, 0.23438] nA
Bias Current (to -80.00 mV) -0.0173 nA
Testing Temperature 34.0 °C
Stability Interval [-1.5625, 15.0] nA
AP 1-2 Amplitude Drop 0.9864 mV
AP 1 Steady State Amplitude Change 0.7163 mV
AP 1 Amplitude 68.7027 mV
AP 1 Width at Half Height 0.7000 ms
AP 1 Width (Peak To Trough) 4.2600 ms
AP 1 Rate of Change Peak to Trough -20.3517 mV/ms
AP 1 AHP Depth 17.9956 mV
AP2 Amplitude 67.7163 mV
AP2 Width at Half Height 0.7000 ms
AP 2 Width (Peak to Trough) 4.3600 ms
AP 2 Rate of Change Peak to Trough -19.7450 mV/ms
AP 2 AHP Depth 18.3717 mV
AP 1-2 Amplitude Change Percent -1.4357 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -2.9813 %
AP 1-2 AHP Depth Percent Change 2.0901 %
Input Resistance 469.7767 MΩ
AP 1 Delay Mean 16.7400 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 52.2500 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 35.8850 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -0.0000 %
Accommodation Rate Mean at Steady State 129.9695 ms
ISI CV 85.4181
ISI Median 34.8100 ms
ISI Burst Mean Change 2.1121 %
Spike Rate (Strong Stimulation) 55.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 5.5500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 21.9000 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 17.2950 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2094.5200 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 114.1838 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 3111.02 µm2
Number of Stems 4.0
Number of Bifurcations 24.0
Number of Branches 51.0
Overall Width 233.736 µm
Overall Height 350.314 µm
Overall Depth 99.24 µm
Average Diameter 0.947101 µm
Total Length 2014.76 µm
Total Surface 5478.03 µm2
Total Volume 2209.51 µm3
Max Euclidean Distance 311.218 µm
Max Path Distance 345.144 µm
Max Branch Order 6.0
Average Contraction 0.970905
Total Fragmentation 581.0
Partition Asymmetry 0.455556
Average Rall's Ratio 1.34038
Average Bifurcation Angle Local 24.086 °
Average Bifurcation Angle Remote 51.7575 °
Fractal Dimension 1.0033
Complexity Summary
State Equations 1193
Optimal Time-Step 0.00770 ms
Relative Complexity 250.18 HH
Model Size
Sections 52
Compartments 98
State Equations 1193
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00770 ms
Optimal Time-Step Error 0.18 %
Optimal Time-Step Benchmark Run Time 250.18 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 1.40 %
Max. Stable Time-Step Benchmark Run Time 481.26 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 14823 Hz
CVODE Steps Per AP 303
CVODE Benchmark Run Time 226.04 HH
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