Layer 5 Continuous Stuttering Nest Basket Cell (2)

Model Type:
Cell
Neurolex IDs: Neocortex basket cell
Neocortex Layer 5
Keywords: continuous stuttering,Layer 5,Fast-spiking, interneuron, GABAergic, inhibitory, neocortex, rat, somatosensory cortex, nest, basket, biophysical, continuous stuttering nest basket cell, Realistic Network, Neuron or other electrically excitable cell, Synapse, Spatio-temporal Activity Patterns, Detailed Neuronal Models
Publication: Markram, et. al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry.
Authors:
H Markram   Eilif Muller   Srikanth Ramaswamy   Michael Reimann   Marwan Abdellah   Carlos Sanchez   Anastasia Ailamaki   Lidia Alonso-Nanclares   Nicolas Antille   Selim Arsever   Guy Kahou   Thomas Berger   Ahmet Bilgili   Nenad Buncic   Athanassia Chalimourda   Giuseppe Chindemi   Jean-Denis Courcol   Fabien Delalondre   Vincent Delattre   Shaul Druckmann   Raphael Dumusc   James Dynes   Stefan Eilemann   Eyal Gal   Michael Gevaert   Jean-Pierre Ghobril   Albert Gidon   Joe Graham   Anirudh Gupta   Valentin Haenel   E Hay   Thomas Heinis   Juan Hernando   Michael Hines   Lida Kanari   Daniel Keller   John Kenyon   Georges Khazen   Yihwa Kim   James King   Zoltan Kisvarday   Pramod Kumbhar   Jean-Vincent Le Bé   Bruno Magalhães   Angel Merchán-Pérez   Julie Meystre   Benjamin Morrice   Jeffrey Muller   Alberto Muñoz-Céspedes   Shruti Muralidhar   Keerthan Muthurasa   Daniel Nachbaur   Taylor Newton   Max Nolte   Aleksandr Ovcharenko   Juan Palacios   Luis Pastor   Rodrigo Perin   Rajnish Ranjan   Imad Riachi   Juan Riquelme   Christian Rössert   Konstantinos Sfyrakis   Ying Shi   Julian Shillcock   Gilad Silberberg   Ricardo Silva   Farhan Tauheed   Martin Telefont   Maria Toledo-Rodriguez   Thomas Tränkler   Werner Van Geit   Jafet Diaz   Richard Walker   Yun Wang   Stefano Zaninetta   Javier DeFelipe   S Hill   Idan Segev   F Schürmann  
Translators: Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL000973
cSTUT189_L5_NBC_4126235f8b_0_0.cell.nml
( view NeuroML )
NMLCH000101
Ca.channel.nml
( view NeuroML )
NMLCH000103
Ca_LVAst.channel.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000105
Im.channel.nml
( view NeuroML )
NMLCH000107
K_Pst.channel.nml
( view NeuroML )
NMLCH000108
K_Tst.channel.nml
( view NeuroML )
NMLCH000109
Nap_Et2.channel.nml
( view NeuroML )
NMLCH000110
NaTa_t.channel.nml
( view NeuroML )
NMLCH000111
NaTs2_t.channel.nml
( view NeuroML )
NMLCH000112
SK_E2.channel.nml
( view NeuroML )
NMLCH000113
SKv3_1.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCH000115
StochKv_deterministic.channel.nml
( view NeuroML )
NMLCN000001
CaDynamics_E2_NML2.nml
( view NeuroML )
Notes: None
Model Id: NMLCL000973
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Accommodating Fast Spikers (aFS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -75.06 mV
Rheobase Current Interval (0.15381, 0.15541] nA
Threshold Current Interval (0.35156, 0.41016] nA
Bias Current (to -70.00 mV) 0.0367 nA
Testing Temperature 34.0 °C
Stability Interval [-1.875, 15.0] nA
AP 1-2 Amplitude Drop 2.7400 mV
AP 1 Steady State Amplitude Change 3.0957 mV
AP 1 Amplitude 85.5292 mV
AP 1 Width at Half Height 0.5500 ms
AP 1 Width (Peak To Trough) 2.7900 ms
AP 1 Rate of Change Peak to Trough -38.3250 mV/ms
AP 1 AHP Depth 21.3975 mV
AP2 Amplitude 82.7892 mV
AP2 Width at Half Height 0.5200 ms
AP 2 Width (Peak to Trough) 2.8100 ms
AP 2 Rate of Change Peak to Trough -37.2220 mV/ms
AP 2 AHP Depth 21.8047 mV
AP 1-2 Amplitude Change Percent -3.2036 %
AP 1-2 Half Width Change Percent -5.4545 %
AP 1-2 Rate of Change Peak to Trough Percent Change -2.8779 %
AP 1-2 AHP Depth Percent Change 1.9031 %
Input Resistance 186.7485 MΩ
AP 1 Delay Mean 6.7900 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 28.4600 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 22.3500 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -5.5556 %
Steady State Accommodation Mean -11.1111 %
Accommodation Rate to Steady State -0.2158 %/ms
Accommodation at Steady State Mean -99.1909 %
Accommodation Rate Mean at Steady State 3218068.7534 ms
ISI CV 45.7015
ISI Median 23.4750 ms
ISI Burst Mean Change 6.2760 %
Spike Rate (Strong Stimulation) 74.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 2.4500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 14.0500 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 12.5200 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2073.3400 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 105.6395 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 7113.44 µm2
Number of Stems 7.0
Number of Bifurcations 32.0
Number of Branches 70.0
Overall Width 375.695 µm
Overall Height 690.351 µm
Overall Depth 176.82 µm
Average Diameter 0.826183 µm
Total Length 4507.78 µm
Total Surface 10133.4 µm2
Total Volume 3988.17 µm3
Max Euclidean Distance 496.306 µm
Max Path Distance 597.056 µm
Max Branch Order 6.0
Average Contraction 0.956206
Total Fragmentation 2463.0
Partition Asymmetry 0.535417
Average Rall's Ratio 0.879545
Average Bifurcation Angle Local 29.5929 °
Average Bifurcation Angle Remote 54.0942 °
Fractal Dimension 1.0085
Complexity Summary
Relative Complexity 717.44 HH
State Equations 2516
Optimal Time-Step 0.00773 ms
Model Size
Sections 71
Compartments 227
State Equations 2516
Variable Time-Step Complexity
CVODE Steady State Step Frequency 19451 Hz
CVODE Steps Per AP 272
CVODE Benchmark Run Time 717.44 HH
Website & Images Copyright NeuroML © 2024 For questions: Contact us Links: Search Test |  ModelDB WS