Layer 1 Continuous Non-accommodating Descending Axon Cell (4)

Model Type:
Cell
Neurolex IDs: Neocortex Layer 1
Keywords: continuous non-accommodating,Layer 1,Rat, somatosensory cortex, neocortex
Publication: Markram, et. al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry.
Authors:
H Markram   Eilif Muller   Srikanth Ramaswamy   Michael Reimann   Marwan Abdellah   Carlos Sanchez   Anastasia Ailamaki   Lidia Alonso-Nanclares   Nicolas Antille   Selim Arsever   Guy Kahou   Thomas Berger   Ahmet Bilgili   Nenad Buncic   Athanassia Chalimourda   Giuseppe Chindemi   Jean-Denis Courcol   Fabien Delalondre   Vincent Delattre   Shaul Druckmann   Raphael Dumusc   James Dynes   Stefan Eilemann   Eyal Gal   Michael Gevaert   Jean-Pierre Ghobril   Albert Gidon   Joe Graham   Anirudh Gupta   Valentin Haenel   E Hay   Thomas Heinis   Juan Hernando   Michael Hines   Lida Kanari   Daniel Keller   John Kenyon   Georges Khazen   Yihwa Kim   James King   Zoltan Kisvarday   Pramod Kumbhar   Jean-Vincent Le Bé   Bruno Magalhães   Angel Merchán-Pérez   Julie Meystre   Benjamin Morrice   Jeffrey Muller   Alberto Muñoz-Céspedes   Shruti Muralidhar   Keerthan Muthurasa   Daniel Nachbaur   Taylor Newton   Max Nolte   Aleksandr Ovcharenko   Juan Palacios   Luis Pastor   Rodrigo Perin   Rajnish Ranjan   Imad Riachi   Juan Riquelme   Christian Rössert   Konstantinos Sfyrakis   Ying Shi   Julian Shillcock   Gilad Silberberg   Ricardo Silva   Farhan Tauheed   Martin Telefont   Maria Toledo-Rodriguez   Thomas Tränkler   Werner Van Geit   Jafet Diaz   Richard Walker   Yun Wang   Stefano Zaninetta   Javier DeFelipe   S Hill   Idan Segev   F Schürmann  
Translators: Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL000755
cNAC187_L1_DAC_8c45268d6a_0_0.cell.nml
( view NeuroML )
NMLCH000101
Ca.channel.nml
( view NeuroML )
NMLCH000103
Ca_LVAst.channel.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000105
Im.channel.nml
( view NeuroML )
NMLCH000107
K_Pst.channel.nml
( view NeuroML )
NMLCH000108
K_Tst.channel.nml
( view NeuroML )
NMLCH000109
Nap_Et2.channel.nml
( view NeuroML )
NMLCH000110
NaTa_t.channel.nml
( view NeuroML )
NMLCH000111
NaTs2_t.channel.nml
( view NeuroML )
NMLCH000112
SK_E2.channel.nml
( view NeuroML )
NMLCH000113
SKv3_1.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCN000001
CaDynamics_E2_NML2.nml
( view NeuroML )
Notes: None
Model Id: NMLCL000755
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -68.84 mV
Rheobase Current Interval (0.03204, 0.03319] nA
Threshold Current Interval (0.23438, 0.29297] nA
Bias Current (to -80.00 mV) -0.0297 nA
Testing Temperature 34.0 °C
Stability Interval [-2.5, 15.0] nA
AP 1-2 Amplitude Drop -0.1025 mV
AP 1 Steady State Amplitude Change 0.0693 mV
AP 1 Amplitude 70.7135 mV
AP 1 Width at Half Height 0.6600 ms
AP 1 Width (Peak To Trough) 6.5700 ms
AP 1 Rate of Change Peak to Trough -13.2943 mV/ms
AP 1 AHP Depth 16.6299 mV
AP2 Amplitude 70.8160 mV
AP2 Width at Half Height 0.6600 ms
AP 2 Width (Peak to Trough) 6.6000 ms
AP 2 Rate of Change Peak to Trough -13.2166 mV/ms
AP 2 AHP Depth 16.4134 mV
AP 1-2 Amplitude Change Percent 0.1449 %
AP 1-2 Half Width Change Percent -0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -0.5845 %
AP 1-2 AHP Depth Percent Change -1.3017 %
Input Resistance 384.3278 MΩ
AP 1 Delay Mean 35.2700 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 97.7600 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 62.7450 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -12.9800 %
Accommodation Rate Mean at Steady State 1638.5944 ms
ISI CV 35.1325
ISI Median 66.4200 ms
ISI Burst Mean Change 0.8161 %
Spike Rate (Strong Stimulation) 31.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 12.4700 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 42.9400 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 31.0550 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2090.9200 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 54.4334 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 9365.89 µm2
Number of Stems 5.0
Number of Bifurcations 38.0
Number of Branches 80.0
Overall Width 196.663 µm
Overall Height 349.249 µm
Overall Depth 188.35 µm
Average Diameter 0.746831 µm
Total Length 4057.04 µm
Total Surface 9353.32 µm2
Total Volume 4390.68 µm3
Max Euclidean Distance 244.904 µm
Max Path Distance 310.953 µm
Max Branch Order 6.0
Average Contraction 0.942246
Total Fragmentation 3056.0
Partition Asymmetry 0.37429
Average Rall's Ratio 1.07016
Average Bifurcation Angle Local 20.2979 °
Average Bifurcation Angle Remote 56.1773 °
Fractal Dimension 1.01167
Complexity Summary
State Equations 2191
Optimal Time-Step 0.00769 ms
Relative Complexity 510.07 HH
Model Size
Sections 81
Compartments 217
State Equations 2191
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00769 ms
Optimal Time-Step Error 0.14 %
Optimal Time-Step Benchmark Run Time 510.07 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 1.10 %
Max. Stable Time-Step Benchmark Run Time 980.43 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 13338 Hz
CVODE Steps Per AP 517
CVODE Benchmark Run Time 477.40 HH
Website & Images Copyright NeuroML © 2019 For questions: Contact us Links: Search Test |  ModelDB WS