Layer 4 Continuous Accommodating Star Pyramidal Cell (2)

Model Type:
Cell
Neurolex IDs: Neocortex Layer 4
Pyramidal Cell
Keywords: continuous accommodating for pyramidal cells,Layer 4,rat, somatosensory cortex, star, pyramidal
Publication: Markram, et. al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry.
Authors:
H Markram   Eilif Muller   Srikanth Ramaswamy   Michael Reimann   Marwan Abdellah   Carlos Sanchez   Anastasia Ailamaki   Lidia Alonso-Nanclares   Nicolas Antille   Selim Arsever   Guy Kahou   Thomas Berger   Ahmet Bilgili   Nenad Buncic   Athanassia Chalimourda   Giuseppe Chindemi   Jean-Denis Courcol   Fabien Delalondre   Vincent Delattre   Shaul Druckmann   Raphael Dumusc   James Dynes   Stefan Eilemann   Eyal Gal   Michael Gevaert   Jean-Pierre Ghobril   Albert Gidon   Joe Graham   Anirudh Gupta   Valentin Haenel   E Hay   Thomas Heinis   Juan Hernando   Michael Hines   Lida Kanari   Daniel Keller   John Kenyon   Georges Khazen   Yihwa Kim   James King   Zoltan Kisvarday   Pramod Kumbhar   Jean-Vincent Le Bé   Bruno Magalhães   Angel Merchán-Pérez   Julie Meystre   Benjamin Morrice   Jeffrey Muller   Alberto Muñoz-Céspedes   Shruti Muralidhar   Keerthan Muthurasa   Daniel Nachbaur   Taylor Newton   Max Nolte   Aleksandr Ovcharenko   Juan Palacios   Luis Pastor   Rodrigo Perin   Rajnish Ranjan   Imad Riachi   Juan Riquelme   Christian Rössert   Konstantinos Sfyrakis   Ying Shi   Julian Shillcock   Gilad Silberberg   Ricardo Silva   Farhan Tauheed   Martin Telefont   Maria Toledo-Rodriguez   Thomas Tränkler   Werner Van Geit   Jafet Diaz   Richard Walker   Yun Wang   Stefano Zaninetta   Javier DeFelipe   S Hill   Idan Segev   F Schürmann  
Translators: Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL000648
cADpyr230_L4_SP_1c98df1fde_0_0.cell.nml
( view NeuroML )
NMLCH000102
Ca_HVA.channel.nml
( view NeuroML )
NMLCH000103
Ca_LVAst.channel.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000105
Im.channel.nml
( view NeuroML )
NMLCH000107
K_Pst.channel.nml
( view NeuroML )
NMLCH000108
K_Tst.channel.nml
( view NeuroML )
NMLCH000109
Nap_Et2.channel.nml
( view NeuroML )
NMLCH000110
NaTa_t.channel.nml
( view NeuroML )
NMLCH000111
NaTs2_t.channel.nml
( view NeuroML )
NMLCH000112
SK_E2.channel.nml
( view NeuroML )
NMLCH000113
SKv3_1.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCN000001
CaDynamics_E2_NML2.nml
( view NeuroML )
Notes: None
Model Id: NMLCL000648
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -73.00 mV
Rheobase Current Interval (0.05493, 0.05722] nA
Threshold Current Interval (0.52734, 0.58594] nA
Bias Current (to -80.00 mV) -0.0321 nA
Testing Temperature 34.0 °C
Stability Interval [-4.375, 15.0] nA
AP 1-2 Amplitude Drop 1.9857 mV
AP 1 Steady State Amplitude Change 1.1471 mV
AP 1 Amplitude 81.3928 mV
AP 1 Width at Half Height 0.8500 ms
AP 1 Width (Peak To Trough) 18.2800 ms
AP 1 Rate of Change Peak to Trough -4.8839 mV/ms
AP 1 AHP Depth 7.8851 mV
AP2 Amplitude 79.4070 mV
AP2 Width at Half Height 0.8400 ms
AP 2 Width (Peak to Trough) 22.2700 ms
AP 2 Rate of Change Peak to Trough -4.0212 mV/ms
AP 2 AHP Depth 10.1445 mV
AP 1-2 Amplitude Change Percent -2.4397 %
AP 1-2 Half Width Change Percent -1.1765 %
AP 1-2 Rate of Change Peak to Trough Percent Change -17.6649 %
AP 1-2 AHP Depth Percent Change 28.6537 %
Input Resistance 213.9113 MΩ
AP 1 Delay Mean 50.2400 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 142.0400 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 161.9600 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -66.6667 %
Steady State Accommodation Mean -33.3333 %
Accommodation Rate to Steady State -0.0486 %/ms
Accommodation at Steady State Mean -70.1711 %
Accommodation Rate Mean at Steady State 10.0000 ms
ISI CV 3.3793
ISI Median 324.7600 ms
ISI Burst Mean Change 152.8540 %
Spike Rate (Strong Stimulation) 6.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 16.6500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 50.2100 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 48.2200 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2090.5300 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 82.5240 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 1843.05 µm2
Number of Stems 6.0
Number of Bifurcations 32.0
Number of Branches 69.0
Overall Width 230.451 µm
Overall Height 712.559 µm
Overall Depth 180.47 µm
Average Diameter 0.761046 µm
Total Length 4289.83 µm
Total Surface 9831.18 µm2
Total Volume 2400.81 µm3
Max Euclidean Distance 733.769 µm
Max Path Distance 753.471 µm
Max Branch Order 6.0
Average Contraction 0.978578
Total Fragmentation 1207.0
Partition Asymmetry 0.39747
Average Rall's Ratio 1.35107
Average Bifurcation Angle Local 63.6469 °
Average Bifurcation Angle Remote 61.0757 °
Fractal Dimension 1.00472
Complexity Summary
State Equations 809
Optimal Time-Step 0.00766 ms
Relative Complexity 176.47 HH
Model Size
Sections 70
Compartments 228
State Equations 809
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00766 ms
Optimal Time-Step Error 0.15 %
Optimal Time-Step Benchmark Run Time 176.47 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 0.58 %
Max. Stable Time-Step Benchmark Run Time 337.84 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 16848 Hz
CVODE Steps Per AP 656
CVODE Benchmark Run Time 208.01 HH
Website & Images Copyright NeuroML © 2019 For questions: Contact us Links: Search Test |  ModelDB WS