Layer 4 Continuous Accommodating Bitufted Cell (2)

Model Type:
Neurolex IDs: Neocortex Layer 4
Keywords: continuous accommodating,Layer 4,Rat, somatosensory cortex, bitufted, biophysical, continuous accommodating bitufted cell, Realistic Network, Neuron or other electrically excitable cell, Synapse, Spatio-temporal Activity Patterns, Detailed Neuronal Models
Publication: Markram, et. al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry.
H Markram   Eilif Muller   Srikanth Ramaswamy   Michael Reimann   Marwan Abdellah   Carlos Sanchez   Anastasia Ailamaki   Lidia Alonso-Nanclares   Nicolas Antille   Selim Arsever   Guy Kahou   Thomas Berger   Ahmet Bilgili   Nenad Buncic   Athanassia Chalimourda   Giuseppe Chindemi   Jean-Denis Courcol   Fabien Delalondre   Vincent Delattre   Shaul Druckmann   Raphael Dumusc   James Dynes   Stefan Eilemann   Eyal Gal   Michael Gevaert   Jean-Pierre Ghobril   Albert Gidon   Joe Graham   Anirudh Gupta   Valentin Haenel   E Hay   Thomas Heinis   Juan Hernando   Michael Hines   Lida Kanari   Daniel Keller   John Kenyon   Georges Khazen   Yihwa Kim   James King   Zoltan Kisvarday   Pramod Kumbhar   Jean-Vincent Le Bé   Bruno Magalhães   Angel Merchán-Pérez   Julie Meystre   Benjamin Morrice   Jeffrey Muller   Alberto Muñoz-Céspedes   Shruti Muralidhar   Keerthan Muthurasa   Daniel Nachbaur   Taylor Newton   Max Nolte   Aleksandr Ovcharenko   Juan Palacios   Luis Pastor   Rodrigo Perin   Rajnish Ranjan   Imad Riachi   Juan Riquelme   Christian Rössert   Konstantinos Sfyrakis   Ying Shi   Julian Shillcock   Gilad Silberberg   Ricardo Silva   Farhan Tauheed   Martin Telefont   Maria Toledo-Rodriguez   Thomas Tränkler   Werner Van Geit   Jafet Diaz   Richard Walker   Yun Wang   Stefano Zaninetta   Javier DeFelipe   S Hill   Idan Segev   F Schürmann  
Translators: Padraig Gleeson  
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Notes: Segment 1133 had duplicated coordinates. Moved it to the midpoint of neighbouring segments.
Model Id: NMLCL000513
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Delayed Regular Spikers (dRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -71.06 mV
Rheobase Current Interval (0.01282, 0.01373] nA
Threshold Current Interval (0.17578, 0.23438] nA
Bias Current (to -80.00 mV) -0.0098 nA
Testing Temperature 34.0 °C
Stability Interval [-1.5625, 15.0] nA
AP 1-2 Amplitude Drop 0.2165 mV
AP 1 Steady State Amplitude Change 0.3213 mV
AP 1 Amplitude 86.2807 mV
AP 1 Width at Half Height 0.5900 ms
AP 1 Width (Peak To Trough) 2.9800 ms
AP 1 Rate of Change Peak to Trough -34.4848 mV/ms
AP 1 AHP Depth 16.4840 mV
AP2 Amplitude 86.0642 mV
AP2 Width at Half Height 0.5800 ms
AP 2 Width (Peak to Trough) 3.0300 ms
AP 2 Rate of Change Peak to Trough -33.9110 mV/ms
AP 2 AHP Depth 16.6862 mV
AP 1-2 Amplitude Change Percent -0.2510 %
AP 1-2 Half Width Change Percent -1.6949 %
AP 1-2 Rate of Change Peak to Trough Percent Change -1.6639 %
AP 1-2 AHP Depth Percent Change 1.2265 %
Input Resistance 922.7788 MΩ
AP 1 Delay Mean 84.2500 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 173.3000 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 91.3650 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -25.0000 %
Steady State Accommodation Mean -25.0000 %
Accommodation Rate to Steady State -0.0190 %/ms
Accommodation at Steady State Mean -51.9093 %
Accommodation Rate Mean at Steady State 790.4696 ms
ISI CV 5.1437
ISI Median 142.4950 ms
ISI Burst Mean Change 5.1993 %
Spike Rate (Strong Stimulation) 14.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 28.8000 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 60.9700 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 33.2200 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2145.3100 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 77.9004 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6347.0 µm2
Number of Stems 4.0
Number of Bifurcations 24.0
Number of Branches 51.0
Overall Width 262.635 µm
Overall Height 521.169 µm
Overall Depth 228.63 µm
Average Diameter 0.684643 µm
Total Length 3841.01 µm
Total Surface 7281.98 µm2
Total Volume 2799.65 µm3
Max Euclidean Distance 438.234 µm
Max Path Distance 492.741 µm
Max Branch Order 5.0
Average Contraction 0.954714
Total Fragmentation 1477.0
Partition Asymmetry 0.468452
Average Rall's Ratio 1.06357
Average Bifurcation Angle Local 52.1526 °
Average Bifurcation Angle Remote 79.3756 °
Fractal Dimension 1.00703
Complexity Summary
Relative Complexity 437.01 HH
State Equations 1941
Optimal Time-Step 0.00777 ms
Model Size
Sections 52
Compartments 192
State Equations 1941
Variable Time-Step Complexity
CVODE Steady State Step Frequency 15235 Hz
CVODE Steps Per AP 367
CVODE Benchmark Run Time 437.01 HH
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