Layer 5 Burst Non-accommodating Small Basket Cell (2)

Model Type:
Cell
Neurolex IDs: Neocortex basket cell
Neocortex Layer 5
Keywords: burst non-accommodating,Layer 5,Fast-spiking, interneuron, GABAergic, inhibitory, neocortex, rat, somatosensory cortex, small, basket
Publication: Markram, et. al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry.
Authors:
H Markram   Eilif Muller   Srikanth Ramaswamy   Michael Reimann   Marwan Abdellah   Carlos Sanchez   Anastasia Ailamaki   Lidia Alonso-Nanclares   Nicolas Antille   Selim Arsever   Guy Kahou   Thomas Berger   Ahmet Bilgili   Nenad Buncic   Athanassia Chalimourda   Giuseppe Chindemi   Jean-Denis Courcol   Fabien Delalondre   Vincent Delattre   Shaul Druckmann   Raphael Dumusc   James Dynes   Stefan Eilemann   Eyal Gal   Michael Gevaert   Jean-Pierre Ghobril   Albert Gidon   Joe Graham   Anirudh Gupta   Valentin Haenel   E Hay   Thomas Heinis   Juan Hernando   Michael Hines   Lida Kanari   Daniel Keller   John Kenyon   Georges Khazen   Yihwa Kim   James King   Zoltan Kisvarday   Pramod Kumbhar   Jean-Vincent Le Bé   Bruno Magalhães   Angel Merchán-Pérez   Julie Meystre   Benjamin Morrice   Jeffrey Muller   Alberto Muñoz-Céspedes   Shruti Muralidhar   Keerthan Muthurasa   Daniel Nachbaur   Taylor Newton   Max Nolte   Aleksandr Ovcharenko   Juan Palacios   Luis Pastor   Rodrigo Perin   Rajnish Ranjan   Imad Riachi   Juan Riquelme   Christian Rössert   Konstantinos Sfyrakis   Ying Shi   Julian Shillcock   Gilad Silberberg   Ricardo Silva   Farhan Tauheed   Martin Telefont   Maria Toledo-Rodriguez   Thomas Tränkler   Werner Van Geit   Jafet Diaz   Richard Walker   Yun Wang   Stefano Zaninetta   Javier DeFelipe   S Hill   Idan Segev   F Schürmann  
Translators: Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL000373
bNAC219_L5_SBC_30bda13a76_0_0.cell.nml
( view NeuroML )
NMLCH000101
Ca.channel.nml
( view NeuroML )
NMLCH000103
Ca_LVAst.channel.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000105
Im.channel.nml
( view NeuroML )
NMLCH000107
K_Pst.channel.nml
( view NeuroML )
NMLCH000108
K_Tst.channel.nml
( view NeuroML )
NMLCH000109
Nap_Et2.channel.nml
( view NeuroML )
NMLCH000110
NaTa_t.channel.nml
( view NeuroML )
NMLCH000111
NaTs2_t.channel.nml
( view NeuroML )
NMLCH000112
SK_E2.channel.nml
( view NeuroML )
NMLCH000113
SKv3_1.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCN000001
CaDynamics_E2_NML2.nml
( view NeuroML )
Notes: None
Model Id: NMLCL000373
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -70.87 mV
Rheobase Current Interval (0.02335, 0.02403] nA
Threshold Current Interval (0.11719, 0.17578] nA
Bias Current (to -80.00 mV) -0.0177 nA
Testing Temperature 34.0 °C
Stability Interval [-1.5625, 15.0] nA
AP 1-2 Amplitude Drop 0.5032 mV
AP 1 Steady State Amplitude Change 3.6754 mV
AP 1 Amplitude 61.4226 mV
AP 1 Width at Half Height 0.7700 ms
AP 1 Width (Peak To Trough) 3.5900 ms
AP 1 Rate of Change Peak to Trough -20.5376 mV/ms
AP 1 AHP Depth 12.3075 mV
AP2 Amplitude 60.9194 mV
AP2 Width at Half Height 0.7900 ms
AP 2 Width (Peak to Trough) 3.6300 ms
AP 2 Rate of Change Peak to Trough -20.1872 mV/ms
AP 2 AHP Depth 12.3602 mV
AP 1-2 Amplitude Change Percent -0.8193 %
AP 1-2 Half Width Change Percent 2.5974 %
AP 1-2 Rate of Change Peak to Trough Percent Change -1.7063 %
AP 1-2 AHP Depth Percent Change 0.4279 %
Input Resistance 518.8969 MΩ
AP 1 Delay Mean 28.7600 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 62.7500 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 41.0700 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -40.0000 %
Steady State Accommodation Mean -40.0000 %
Accommodation Rate to Steady State -0.1068 %/ms
Accommodation at Steady State Mean -82.8265 %
Accommodation Rate Mean at Steady State 127.0753 ms
ISI CV 3.6191
ISI Median 144.2400 ms
ISI Burst Mean Change 41.6593 %
Spike Rate (Strong Stimulation) 12.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 9.8700 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 25.5300 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 17.9150 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2054.2100 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6826.28 µm2
Number of Stems 4.0
Number of Bifurcations 20.0
Number of Branches 43.0
Overall Width 289.265 µm
Overall Height 501.326 µm
Overall Depth 122.24 µm
Average Diameter 0.90539 µm
Total Length 2326.84 µm
Total Surface 5906.32 µm2
Total Volume 3652.26 µm3
Max Euclidean Distance 341.699 µm
Max Path Distance 376.697 µm
Max Branch Order 7.0
Average Contraction 0.963697
Total Fragmentation 1102.0
Partition Asymmetry 0.446032
Average Rall's Ratio 0.521765
Average Bifurcation Angle Local 39.8479 °
Average Bifurcation Angle Remote 52.6732 °
Fractal Dimension 1.00901
Complexity Summary
State Equations 1221
Optimal Time-Step 0.00540 ms
Relative Complexity 404.76 HH
Model Size
Sections 44
Compartments 120
State Equations 1221
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00540 ms
Optimal Time-Step Error 0.24 %
Optimal Time-Step Benchmark Run Time 404.76 HH
 
Maximum Stable Time-Step 0.03125 ms
Maximum Stable Time-Step Error 1.57 %
Max. Stable Time-Step Benchmark Run Time 1092.00 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 15382 Hz
CVODE Steps Per AP 410
CVODE Benchmark Run Time 279.88 HH
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