Layer 4 Burst Non-accommodating Small Basket Cell (3)

Model Type:
Cell
Neurolex IDs: Neocortex basket cell
Neocortex Layer 4
Keywords: burst non-accommodating,Layer 4,Fast-spiking, interneuron, GABAergic, inhibitory, neocortex, rat, somatosensory cortex, small, basket, biophysical, burst non-accommodating small basket cell, Realistic Network, Neuron or other electrically excitable cell, Synapse, Spatio-temporal Activity Patterns, Detailed Neuronal Models
Publication: Markram, et. al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry.
Authors:
H Markram   Eilif Muller   Srikanth Ramaswamy   Michael Reimann   Marwan Abdellah   Carlos Sanchez   Anastasia Ailamaki   Lidia Alonso-Nanclares   Nicolas Antille   Selim Arsever   Guy Kahou   Thomas Berger   Ahmet Bilgili   Nenad Buncic   Athanassia Chalimourda   Giuseppe Chindemi   Jean-Denis Courcol   Fabien Delalondre   Vincent Delattre   Shaul Druckmann   Raphael Dumusc   James Dynes   Stefan Eilemann   Eyal Gal   Michael Gevaert   Jean-Pierre Ghobril   Albert Gidon   Joe Graham   Anirudh Gupta   Valentin Haenel   E Hay   Thomas Heinis   Juan Hernando   Michael Hines   Lida Kanari   Daniel Keller   John Kenyon   Georges Khazen   Yihwa Kim   James King   Zoltan Kisvarday   Pramod Kumbhar   Jean-Vincent Le Bé   Bruno Magalhães   Angel Merchán-Pérez   Julie Meystre   Benjamin Morrice   Jeffrey Muller   Alberto Muñoz-Céspedes   Shruti Muralidhar   Keerthan Muthurasa   Daniel Nachbaur   Taylor Newton   Max Nolte   Aleksandr Ovcharenko   Juan Palacios   Luis Pastor   Rodrigo Perin   Rajnish Ranjan   Imad Riachi   Juan Riquelme   Christian Rössert   Konstantinos Sfyrakis   Ying Shi   Julian Shillcock   Gilad Silberberg   Ricardo Silva   Farhan Tauheed   Martin Telefont   Maria Toledo-Rodriguez   Thomas Tränkler   Werner Van Geit   Jafet Diaz   Richard Walker   Yun Wang   Stefano Zaninetta   Javier DeFelipe   S Hill   Idan Segev   F Schürmann  
Translators: Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL000354
bNAC219_L4_SBC_3845e9299a_0_0.cell.nml
( view NeuroML )
NMLCH000101
Ca.channel.nml
( view NeuroML )
NMLCH000103
Ca_LVAst.channel.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000105
Im.channel.nml
( view NeuroML )
NMLCH000107
K_Pst.channel.nml
( view NeuroML )
NMLCH000108
K_Tst.channel.nml
( view NeuroML )
NMLCH000109
Nap_Et2.channel.nml
( view NeuroML )
NMLCH000110
NaTa_t.channel.nml
( view NeuroML )
NMLCH000111
NaTs2_t.channel.nml
( view NeuroML )
NMLCH000112
SK_E2.channel.nml
( view NeuroML )
NMLCH000113
SKv3_1.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCN000001
CaDynamics_E2_NML2.nml
( view NeuroML )
Notes: None
Model Id: NMLCL000354
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -71.17 mV
Rheobase Current Interval (0.02678, 0.02747] nA
Threshold Current Interval (0.11719, 0.17578] nA
Bias Current (to -80.00 mV) -0.0127 nA
Testing Temperature 34.0 °C
Stability Interval [-0.9375, 15.0] nA
AP 1-2 Amplitude Drop 0.1447 mV
AP 1 Steady State Amplitude Change 5.6685 mV
AP 1 Amplitude 73.2736 mV
AP 1 Width at Half Height 0.4800 ms
AP 1 Width (Peak To Trough) 2.1700 ms
AP 1 Rate of Change Peak to Trough -44.3009 mV/ms
AP 1 AHP Depth 22.8593 mV
AP2 Amplitude 73.1289 mV
AP2 Width at Half Height 0.4800 ms
AP 2 Width (Peak to Trough) 2.1600 ms
AP 2 Rate of Change Peak to Trough -44.4595 mV/ms
AP 2 AHP Depth 22.9036 mV
AP 1-2 Amplitude Change Percent -0.1975 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change 0.3581 %
AP 1-2 AHP Depth Percent Change 0.1939 %
Input Resistance 719.6172 MΩ
AP 1 Delay Mean 17.9800 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 44.4000 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 28.2050 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -28.5714 %
Steady State Accommodation Mean -28.5714 %
Accommodation Rate to Steady State -0.1049 %/ms
Accommodation at Steady State Mean -80.1446 %
Accommodation Rate Mean at Steady State 118.3427 ms
ISI CV 4.1302
ISI Median 90.0450 ms
ISI Burst Mean Change 13.5125 %
Spike Rate (Strong Stimulation) 41.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 6.2200 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 19.1700 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 13.4700 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2015.5400 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 125.3076 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5550.0 µm2
Number of Stems 8.0
Number of Bifurcations 17.0
Number of Branches 41.0
Overall Width 277.186 µm
Overall Height 311.959 µm
Overall Depth 116.35 µm
Average Diameter 0.489496 µm
Total Length 2848.31 µm
Total Surface 3899.67 µm2
Total Volume 2006.12 µm3
Max Euclidean Distance 215.565 µm
Max Path Distance 248.627 µm
Max Branch Order 4.0
Average Contraction 0.934254
Total Fragmentation 2328.0
Partition Asymmetry 0.45098
Average Rall's Ratio 0.615
Average Bifurcation Angle Local 38.4297 °
Average Bifurcation Angle Remote 65.2389 °
Fractal Dimension 1.0136
Complexity Summary
Relative Complexity 318.01 HH
State Equations 1421
Optimal Time-Step 0.00777 ms
Model Size
Sections 42
Compartments 140
State Equations 1421
Variable Time-Step Complexity
CVODE Steady State Step Frequency 13389 Hz
CVODE Steps Per AP 514
CVODE Benchmark Run Time 318.01 HH
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