Layer 1 Burst Non-accommodating Neurogliaform Cell with dense axonal arborization (4)

Model Type:
Cell
Neurolex IDs: Neocortex Layer 1
Keywords: burst non-accommodating,Layer 1,GABAergic, inhibitory, neocortex, rat, somatosensory cortex, neocortex, neurogliaform, dense axonal arborization
Publication: Markram, et. al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry.
Authors:
H Markram   Eilif Muller   Srikanth Ramaswamy   Michael Reimann   Marwan Abdellah   Carlos Sanchez   Anastasia Ailamaki   Lidia Alonso-Nanclares   Nicolas Antille   Selim Arsever   Guy Kahou   Thomas Berger   Ahmet Bilgili   Nenad Buncic   Athanassia Chalimourda   Giuseppe Chindemi   Jean-Denis Courcol   Fabien Delalondre   Vincent Delattre   Shaul Druckmann   Raphael Dumusc   James Dynes   Stefan Eilemann   Eyal Gal   Michael Gevaert   Jean-Pierre Ghobril   Albert Gidon   Joe Graham   Anirudh Gupta   Valentin Haenel   E Hay   Thomas Heinis   Juan Hernando   Michael Hines   Lida Kanari   Daniel Keller   John Kenyon   Georges Khazen   Yihwa Kim   James King   Zoltan Kisvarday   Pramod Kumbhar   Jean-Vincent Le Bé   Bruno Magalhães   Angel Merchán-Pérez   Julie Meystre   Benjamin Morrice   Jeffrey Muller   Alberto Muñoz-Céspedes   Shruti Muralidhar   Keerthan Muthurasa   Daniel Nachbaur   Taylor Newton   Max Nolte   Aleksandr Ovcharenko   Juan Palacios   Luis Pastor   Rodrigo Perin   Rajnish Ranjan   Imad Riachi   Juan Riquelme   Christian Rössert   Konstantinos Sfyrakis   Ying Shi   Julian Shillcock   Gilad Silberberg   Ricardo Silva   Farhan Tauheed   Martin Telefont   Maria Toledo-Rodriguez   Thomas Tränkler   Werner Van Geit   Jafet Diaz   Richard Walker   Yun Wang   Stefano Zaninetta   Javier DeFelipe   S Hill   Idan Segev   F Schürmann  
Translators: Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL000285
bNAC219_L1_NGCDA_b030a58a66_0_0.cell.nml
( view NeuroML )
NMLCH000101
Ca.channel.nml
( view NeuroML )
NMLCH000103
Ca_LVAst.channel.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000105
Im.channel.nml
( view NeuroML )
NMLCH000107
K_Pst.channel.nml
( view NeuroML )
NMLCH000108
K_Tst.channel.nml
( view NeuroML )
NMLCH000109
Nap_Et2.channel.nml
( view NeuroML )
NMLCH000110
NaTa_t.channel.nml
( view NeuroML )
NMLCH000111
NaTs2_t.channel.nml
( view NeuroML )
NMLCH000112
SK_E2.channel.nml
( view NeuroML )
NMLCH000113
SKv3_1.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCN000001
CaDynamics_E2_NML2.nml
( view NeuroML )
Notes: None
Model Id: NMLCL000285
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -71.85 mV
Rheobase Current Interval (0.02472, 0.02541] nA
Threshold Current Interval (0.11719, 0.17578] nA
Bias Current (to -80.00 mV) -0.0105 nA
Testing Temperature 34.0 °C
Stability Interval [-0.9375, 15.0] nA
AP 1-2 Amplitude Drop 0.0072 mV
AP 1 Steady State Amplitude Change 3.0490 mV
AP 1 Amplitude 69.9189 mV
AP 1 Width at Half Height 0.5700 ms
AP 1 Width (Peak To Trough) 3.0500 ms
AP 1 Rate of Change Peak to Trough -31.6305 mV/ms
AP 1 AHP Depth 26.5541 mV
AP2 Amplitude 69.9117 mV
AP2 Width at Half Height 0.5800 ms
AP 2 Width (Peak to Trough) 3.0500 ms
AP 2 Rate of Change Peak to Trough -31.5302 mV/ms
AP 2 AHP Depth 26.2555 mV
AP 1-2 Amplitude Change Percent -0.0103 %
AP 1-2 Half Width Change Percent 1.7544 %
AP 1-2 Rate of Change Peak to Trough Percent Change -0.3170 %
AP 1-2 AHP Depth Percent Change -1.1244 %
Input Resistance 807.9786 MΩ
AP 1 Delay Mean 17.9100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 46.5000 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 31.9900 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -20.0000 %
Steady State Accommodation Mean -40.0000 %
Accommodation Rate to Steady State -0.1302 %/ms
Accommodation at Steady State Mean -84.2442 %
Accommodation Rate Mean at Steady State 103.1407 ms
ISI CV 3.7267
ISI Median 122.3600 ms
ISI Burst Mean Change 23.7845 %
Spike Rate (Strong Stimulation) 22.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 6.6600 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 21.0700 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 14.9450 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2040.8000 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5750.6 µm2
Number of Stems 6.0
Number of Bifurcations 18.0
Number of Branches 41.0
Overall Width 94.6075 µm
Overall Height 135.108 µm
Overall Depth 110.19 µm
Average Diameter 1.00852 µm
Total Length 1108.53 µm
Total Surface 3136.08 µm2
Total Volume 2184.77 µm3
Max Euclidean Distance 126.446 µm
Max Path Distance 169.888 µm
Max Branch Order 5.0
Average Contraction 0.942939
Total Fragmentation 745.0
Partition Asymmetry 0.527778
Average Rall's Ratio 1.94409
Average Bifurcation Angle Local 50.1019 °
Average Bifurcation Angle Remote 59.1407 °
Fractal Dimension 1.01479
Complexity Summary
State Equations 581
Optimal Time-Step 0.00794 ms
Relative Complexity 127.86 HH
Model Size
Sections 42
Compartments 56
State Equations 581
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00794 ms
Optimal Time-Step Error 0.19 %
Optimal Time-Step Benchmark Run Time 127.86 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 1.90 %
Max. Stable Time-Step Benchmark Run Time 253.68 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 14507 Hz
CVODE Steps Per AP 348
CVODE Benchmark Run Time 120.07 HH
Website & Images Copyright NeuroML © 2019 For questions: Contact us Links: Search Test |  ModelDB WS