Layer 1 Burst Non-accommodating Descending Axon Cell (2)

Model Type:
Cell
Neurolex IDs: Neocortex Layer 1
Keywords: burst non-accommodating,Layer 1,Rat, somatosensory cortex, neocortex
Publication: Markram, et. al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry.
Authors:
H Markram   Eilif Muller   Srikanth Ramaswamy   Michael Reimann   Marwan Abdellah   Carlos Sanchez   Anastasia Ailamaki   Lidia Alonso-Nanclares   Nicolas Antille   Selim Arsever   Guy Kahou   Thomas Berger   Ahmet Bilgili   Nenad Buncic   Athanassia Chalimourda   Giuseppe Chindemi   Jean-Denis Courcol   Fabien Delalondre   Vincent Delattre   Shaul Druckmann   Raphael Dumusc   James Dynes   Stefan Eilemann   Eyal Gal   Michael Gevaert   Jean-Pierre Ghobril   Albert Gidon   Joe Graham   Anirudh Gupta   Valentin Haenel   E Hay   Thomas Heinis   Juan Hernando   Michael Hines   Lida Kanari   Daniel Keller   John Kenyon   Georges Khazen   Yihwa Kim   James King   Zoltan Kisvarday   Pramod Kumbhar   Jean-Vincent Le Bé   Bruno Magalhães   Angel Merchán-Pérez   Julie Meystre   Benjamin Morrice   Jeffrey Muller   Alberto Muñoz-Céspedes   Shruti Muralidhar   Keerthan Muthurasa   Daniel Nachbaur   Taylor Newton   Max Nolte   Aleksandr Ovcharenko   Juan Palacios   Luis Pastor   Rodrigo Perin   Rajnish Ranjan   Imad Riachi   Juan Riquelme   Christian Rössert   Konstantinos Sfyrakis   Ying Shi   Julian Shillcock   Gilad Silberberg   Ricardo Silva   Farhan Tauheed   Martin Telefont   Maria Toledo-Rodriguez   Thomas Tränkler   Werner Van Geit   Jafet Diaz   Richard Walker   Yun Wang   Stefano Zaninetta   Javier DeFelipe   S Hill   Idan Segev   F Schürmann  
Translators: Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL000273
bNAC219_L1_DAC_56906d7a99_0_0.cell.nml
( view NeuroML )
NMLCH000101
Ca.channel.nml
( view NeuroML )
NMLCH000103
Ca_LVAst.channel.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000105
Im.channel.nml
( view NeuroML )
NMLCH000107
K_Pst.channel.nml
( view NeuroML )
NMLCH000108
K_Tst.channel.nml
( view NeuroML )
NMLCH000109
Nap_Et2.channel.nml
( view NeuroML )
NMLCH000110
NaTa_t.channel.nml
( view NeuroML )
NMLCH000111
NaTs2_t.channel.nml
( view NeuroML )
NMLCH000112
SK_E2.channel.nml
( view NeuroML )
NMLCH000113
SKv3_1.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCN000001
CaDynamics_E2_NML2.nml
( view NeuroML )
Notes: None
Model Id: NMLCL000273
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Accommodating Fast Spikers (aFS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -71.87 mV
Rheobase Current Interval (0.03113, 0.03159] nA
Threshold Current Interval (0.05859, 0.11719] nA
Bias Current (to -80.00 mV) -0.0112 nA
Testing Temperature 34.0 °C
Stability Interval [-0.625, 15.0] nA
AP 1-2 Amplitude Drop 0.0161 mV
AP 1 Steady State Amplitude Change 5.0754 mV
AP 1 Amplitude 74.9862 mV
AP 1 Width at Half Height 0.4900 ms
AP 1 Width (Peak To Trough) 2.3300 ms
AP 1 Rate of Change Peak to Trough -42.7029 mV/ms
AP 1 AHP Depth 24.5115 mV
AP2 Amplitude 74.9702 mV
AP2 Width at Half Height 0.4800 ms
AP 2 Width (Peak to Trough) 2.3300 ms
AP 2 Rate of Change Peak to Trough -42.7542 mV/ms
AP 2 AHP Depth 24.6471 mV
AP 1-2 Amplitude Change Percent -0.0214 %
AP 1-2 Half Width Change Percent -2.0408 %
AP 1-2 Rate of Change Peak to Trough Percent Change 0.1201 %
AP 1-2 AHP Depth Percent Change 0.5532 %
Input Resistance 762.6008 MΩ
AP 1 Delay Mean 11.9700 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 32.3800 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 22.4300 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -33.3333 %
Steady State Accommodation Mean -33.3333 %
Accommodation Rate to Steady State -0.1361 %/ms
Accommodation at Steady State Mean -88.1272 %
Accommodation Rate Mean at Steady State 80.3394 ms
ISI CV 3.8946
ISI Median 102.1800 ms
ISI Burst Mean Change 19.7942 %
Spike Rate (Strong Stimulation) 52.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 4.3900 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 15.8200 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 11.7100 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2023.9900 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6496.34 µm2
Number of Stems 8.0
Number of Bifurcations 18.0
Number of Branches 43.0
Overall Width 192.408 µm
Overall Height 235.751 µm
Overall Depth 167.92 µm
Average Diameter 0.446111 µm
Total Length 2212.31 µm
Total Surface 3127.42 µm2
Total Volume 2230.65 µm3
Max Euclidean Distance 233.963 µm
Max Path Distance 267.677 µm
Max Branch Order 5.0
Average Contraction 0.939087
Total Fragmentation 1553.0
Partition Asymmetry 0.388889
Average Rall's Ratio 1.3355
Average Bifurcation Angle Local 43.323 °
Average Bifurcation Angle Remote 56.858 °
Fractal Dimension 1.01015
Complexity Summary
State Equations 1141
Optimal Time-Step 0.00775 ms
Relative Complexity 258.68 HH
Model Size
Sections 44
Compartments 112
State Equations 1141
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00775 ms
Optimal Time-Step Error 0.22 %
Optimal Time-Step Benchmark Run Time 258.68 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 1.10 %
Max. Stable Time-Step Benchmark Run Time 500.83 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 13054 Hz
CVODE Steps Per AP 425
CVODE Benchmark Run Time 228.00 HH
Website & Images Copyright NeuroML © 2019 For questions: Contact us Links: Search Test |  ModelDB WS