Layer 5 Burst Accommodating Martinotti Cell (4)

Model Type:
Cell
Neurolex IDs: Martinotti Cell
Neocortex Layer 5
Keywords: burst accommodating,Layer 5,GABAergic, inhibitory, neocortex, rat, somatosensory cortex, Martinotti
Publication: Markram, et. al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry.
Authors:
H Markram   Eilif Muller   Srikanth Ramaswamy   Michael Reimann   Marwan Abdellah   Carlos Sanchez   Anastasia Ailamaki   Lidia Alonso-Nanclares   Nicolas Antille   Selim Arsever   Guy Kahou   Thomas Berger   Ahmet Bilgili   Nenad Buncic   Athanassia Chalimourda   Giuseppe Chindemi   Jean-Denis Courcol   Fabien Delalondre   Vincent Delattre   Shaul Druckmann   Raphael Dumusc   James Dynes   Stefan Eilemann   Eyal Gal   Michael Gevaert   Jean-Pierre Ghobril   Albert Gidon   Joe Graham   Anirudh Gupta   Valentin Haenel   E Hay   Thomas Heinis   Juan Hernando   Michael Hines   Lida Kanari   Daniel Keller   John Kenyon   Georges Khazen   Yihwa Kim   James King   Zoltan Kisvarday   Pramod Kumbhar   Jean-Vincent Le Bé   Bruno Magalhães   Angel Merchán-Pérez   Julie Meystre   Benjamin Morrice   Jeffrey Muller   Alberto Muñoz-Céspedes   Shruti Muralidhar   Keerthan Muthurasa   Daniel Nachbaur   Taylor Newton   Max Nolte   Aleksandr Ovcharenko   Juan Palacios   Luis Pastor   Rodrigo Perin   Rajnish Ranjan   Imad Riachi   Juan Riquelme   Christian Rössert   Konstantinos Sfyrakis   Ying Shi   Julian Shillcock   Gilad Silberberg   Ricardo Silva   Farhan Tauheed   Martin Telefont   Maria Toledo-Rodriguez   Thomas Tränkler   Werner Van Geit   Jafet Diaz   Richard Walker   Yun Wang   Stefano Zaninetta   Javier DeFelipe   S Hill   Idan Segev   F Schürmann  
Translators: Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL000160
bAC217_L5_MC_c135727743_0_0.cell.nml
( view NeuroML )
NMLCH000101
Ca.channel.nml
( view NeuroML )
NMLCH000103
Ca_LVAst.channel.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000105
Im.channel.nml
( view NeuroML )
NMLCH000107
K_Pst.channel.nml
( view NeuroML )
NMLCH000108
K_Tst.channel.nml
( view NeuroML )
NMLCH000109
Nap_Et2.channel.nml
( view NeuroML )
NMLCH000110
NaTa_t.channel.nml
( view NeuroML )
NMLCH000111
NaTs2_t.channel.nml
( view NeuroML )
NMLCH000112
SK_E2.channel.nml
( view NeuroML )
NMLCH000113
SKv3_1.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCN000001
CaDynamics_E2_NML2.nml
( view NeuroML )
Notes: None
Model Id: NMLCL000160
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Bursters (B)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -71.17 mV
Rheobase Current Interval (0.06454, 0.06592] nA
Threshold Current Interval (0.29297, 0.35156] nA
Bias Current (to -80.00 mV) -0.0284 nA
Testing Temperature 34.0 °C
Stability Interval [-2.5, 15.0] nA
AP 1-2 Amplitude Drop 2.2480 mV
AP 1 Steady State Amplitude Change 3.8571 mV
AP 1 Amplitude 70.9594 mV
AP 1 Width at Half Height 0.5600 ms
AP 1 Width (Peak To Trough) 6.4000 ms
AP 1 Rate of Change Peak to Trough -13.9756 mV/ms
AP 1 AHP Depth 18.4842 mV
AP2 Amplitude 68.7114 mV
AP2 Width at Half Height 0.5600 ms
AP 2 Width (Peak to Trough) 7.0400 ms
AP 2 Rate of Change Peak to Trough -12.5269 mV/ms
AP 2 AHP Depth 19.4779 mV
AP 1-2 Amplitude Change Percent -3.1679 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -10.3657 %
AP 1-2 AHP Depth Percent Change 5.3758 %
Input Resistance 303.4086 MΩ
AP 1 Delay Mean 18.0400 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 65.0700 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 64.5800 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -50.0000 %
Steady State Accommodation Mean -50.0000 %
Accommodation Rate to Steady State -0.1365 %/ms
Accommodation at Steady State Mean -84.6704 %
Accommodation Rate Mean at Steady State 164.6291 ms
ISI CV 2.9978
ISI Median 220.9250 ms
ISI Burst Mean Change 74.6332 %
Spike Rate (Strong Stimulation) 9.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 6.8800 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 32.2300 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 26.9350 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2041.5100 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6871.46 µm2
Number of Stems 6.0
Number of Bifurcations 31.0
Number of Branches 67.0
Overall Width 343.287 µm
Overall Height 399.232 µm
Overall Depth 210.14 µm
Average Diameter 0.814646 µm
Total Length 5021.31 µm
Total Surface 10159.8 µm2
Total Volume 4193.39 µm3
Max Euclidean Distance 284.53 µm
Max Path Distance 424.93 µm
Max Branch Order 4.0
Average Contraction 0.934465
Total Fragmentation 2681.0
Partition Asymmetry 0.35
Average Rall's Ratio 1.05942
Average Bifurcation Angle Local 17.2401 °
Average Bifurcation Angle Remote 56.8487 °
Fractal Dimension 1.01259
Complexity Summary
State Equations 2561
Optimal Time-Step 0.00787 ms
Relative Complexity 631.03 HH
Model Size
Sections 68
Compartments 254
State Equations 2561
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00787 ms
Optimal Time-Step Error 0.20 %
Optimal Time-Step Benchmark Run Time 631.03 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 2.10 %
Max. Stable Time-Step Benchmark Run Time 1241.88 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 14512 Hz
CVODE Steps Per AP 636
CVODE Benchmark Run Time 681.94 HH
Website & Images Copyright NeuroML © 2021 For questions: Contact us Links: Search Test |  ModelDB WS