Layer 4 Burst Accommodating Martinotti Cell (3)

Model Type:
Cell
Neurolex IDs: Martinotti Cell
Neocortex Layer 4
Keywords: burst accommodating,Layer 4,GABAergic, inhibitory, neocortex, rat, somatosensory cortex, Martinotti
Publication: Markram, et. al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry.
Authors:
H Markram   Eilif Muller   Srikanth Ramaswamy   Michael Reimann   Marwan Abdellah   Carlos Sanchez   Anastasia Ailamaki   Lidia Alonso-Nanclares   Nicolas Antille   Selim Arsever   Guy Kahou   Thomas Berger   Ahmet Bilgili   Nenad Buncic   Athanassia Chalimourda   Giuseppe Chindemi   Jean-Denis Courcol   Fabien Delalondre   Vincent Delattre   Shaul Druckmann   Raphael Dumusc   James Dynes   Stefan Eilemann   Eyal Gal   Michael Gevaert   Jean-Pierre Ghobril   Albert Gidon   Joe Graham   Anirudh Gupta   Valentin Haenel   E Hay   Thomas Heinis   Juan Hernando   Michael Hines   Lida Kanari   Daniel Keller   John Kenyon   Georges Khazen   Yihwa Kim   James King   Zoltan Kisvarday   Pramod Kumbhar   Jean-Vincent Le Bé   Bruno Magalhães   Angel Merchán-Pérez   Julie Meystre   Benjamin Morrice   Jeffrey Muller   Alberto Muñoz-Céspedes   Shruti Muralidhar   Keerthan Muthurasa   Daniel Nachbaur   Taylor Newton   Max Nolte   Aleksandr Ovcharenko   Juan Palacios   Luis Pastor   Rodrigo Perin   Rajnish Ranjan   Imad Riachi   Juan Riquelme   Christian Rössert   Konstantinos Sfyrakis   Ying Shi   Julian Shillcock   Gilad Silberberg   Ricardo Silva   Farhan Tauheed   Martin Telefont   Maria Toledo-Rodriguez   Thomas Tränkler   Werner Van Geit   Jafet Diaz   Richard Walker   Yun Wang   Stefano Zaninetta   Javier DeFelipe   S Hill   Idan Segev   F Schürmann  
Translators: Padraig Gleeson  
Sources:
Files:
Model ID NeuroML File
NMLCL000134
bAC217_L4_MC_3110386c07_0_0.cell.nml
( view NeuroML )
NMLCH000101
Ca.channel.nml
( view NeuroML )
NMLCH000103
Ca_LVAst.channel.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000105
Im.channel.nml
( view NeuroML )
NMLCH000107
K_Pst.channel.nml
( view NeuroML )
NMLCH000108
K_Tst.channel.nml
( view NeuroML )
NMLCH000109
Nap_Et2.channel.nml
( view NeuroML )
NMLCH000110
NaTa_t.channel.nml
( view NeuroML )
NMLCH000111
NaTs2_t.channel.nml
( view NeuroML )
NMLCH000112
SK_E2.channel.nml
( view NeuroML )
NMLCH000113
SKv3_1.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCN000001
CaDynamics_E2_NML2.nml
( view NeuroML )
Notes: None
Model Id: NMLCL000134
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Bursters (B)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -70.96 mV
Rheobase Current Interval (0.08423, 0.08606] nA
Threshold Current Interval (0.41016, 0.46875] nA
Bias Current (to -80.00 mV) -0.0359 nA
Testing Temperature 34.0 °C
Stability Interval [-3.4375, 15.0] nA
AP 1-2 Amplitude Drop 1.6098 mV
AP 1 Steady State Amplitude Change 2.2361 mV
AP 1 Amplitude 70.8627 mV
AP 1 Width at Half Height 0.5700 ms
AP 1 Width (Peak To Trough) 7.4300 ms
AP 1 Rate of Change Peak to Trough -11.8369 mV/ms
AP 1 AHP Depth 17.0853 mV
AP2 Amplitude 69.2529 mV
AP2 Width at Half Height 0.5700 ms
AP 2 Width (Peak to Trough) 7.8000 ms
AP 2 Rate of Change Peak to Trough -11.1429 mV/ms
AP 2 AHP Depth 17.6619 mV
AP 1-2 Amplitude Change Percent -2.2717 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -5.8626 %
AP 1-2 AHP Depth Percent Change 3.3749 %
Input Resistance 240.9957 MΩ
AP 1 Delay Mean 19.7400 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 69.1300 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 57.6250 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -75.0000 %
Steady State Accommodation Mean -50.0000 %
Accommodation Rate to Steady State -0.1459 %/ms
Accommodation at Steady State Mean -84.3029 %
Accommodation Rate Mean at Steady State 155.8467 ms
ISI CV 2.9244
ISI Median 210.8700 ms
ISI Burst Mean Change 33.3468 %
Spike Rate (Strong Stimulation) 10.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 7.1700 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 32.8000 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 27.1650 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2036.5200 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 38.4545 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 8772.39 µm2
Number of Stems 4.0
Number of Bifurcations 38.0
Number of Branches 79.0
Overall Width 247.834 µm
Overall Height 336.207 µm
Overall Depth 277.57 µm
Average Diameter 0.863752 µm
Total Length 5386.96 µm
Total Surface 12955.7 µm2
Total Volume 5416.35 µm3
Max Euclidean Distance 237.727 µm
Max Path Distance 324.781 µm
Max Branch Order 8.0
Average Contraction 0.962697
Total Fragmentation 1405.0
Partition Asymmetry 0.526126
Average Rall's Ratio 1.07548
Average Bifurcation Angle Local 37.2878 °
Average Bifurcation Angle Remote 55.2026 °
Fractal Dimension 1.00499
Complexity Summary
State Equations 2761
Optimal Time-Step 0.00775 ms
Relative Complexity 691.75 HH
Model Size
Sections 80
Compartments 274
State Equations 2761
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00775 ms
Optimal Time-Step Error 0.14 %
Optimal Time-Step Benchmark Run Time 691.75 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 0.93 %
Max. Stable Time-Step Benchmark Run Time 1339.40 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 12536 Hz
CVODE Steps Per AP 646
CVODE Benchmark Run Time 669.23 HH
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