Izhikevich Tonic Spiking Cell

Model Type:
Cell
Neurolex IDs: None
Keywords: , Neuron or other electrically excitable cell, Action Potential Initiation, Activity Patterns, Parameter Fitting, Simplified Models, Tutorial/Teaching, Action Potentials
Publication: Izhikevich (2003) Simple model of spiking neurons
Authors:
EM Izhikevich  
Translators: Padraig Gleeson   Andrew Davison   Vitor Chaud  
Sources:
Files:
Model ID NeuroML File
NMLCL000086
IzhikevichTonicSpiking.cell.nml
( view NeuroML )
Notes: None
Model Id: NMLCL000086
Associated Channels: None
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -70.00 mV
Rheobase Current Interval (2.68478, 2.71111] nA
Threshold Current Interval (6.67969, 6.73828] nA
Bias Current (to -80.00 mV) -5.0000 nA
Testing Temperature 36.0 °C
Stability Interval [-10.0, 15.0] nA
AP 1-2 Amplitude Drop 1.7589 mV
AP 1 Steady State Amplitude Change 3.1114 mV
AP 1 Amplitude 78.1889 mV
AP 1 Width at Half Height 0.1900 ms
AP 1 Width (Peak To Trough) 5.0200 ms
AP 1 Rate of Change Peak to Trough -20.7653 mV/ms
AP 1 AHP Depth 26.0529 mV
AP2 Amplitude 76.4300 mV
AP2 Width at Half Height 0.1800 ms
AP 2 Width (Peak to Trough) 4.6200 ms
AP 2 Rate of Change Peak to Trough -22.9067 mV/ms
AP 2 AHP Depth 29.3988 mV
AP 1-2 Amplitude Change Percent -2.2496 %
AP 1-2 Half Width Change Percent -5.2632 %
AP 1-2 Rate of Change Peak to Trough Percent Change 10.3123 %
AP 1-2 AHP Depth Percent Change 12.8430 %
Input Resistance 1.1415 MΩ
AP 1 Delay Mean 7.6800 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 122.4100 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 119.3700 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -25.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -7.5110 %
Accommodation Rate Mean at Steady State 22.4535 ms
ISI CV 54.7535
ISI Median 124.0400 ms
ISI Burst Mean Change 8.0886 %
Spike Rate (Strong Stimulation) 21.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 2.7200 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 22.2600 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 33.4400 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2407.6700 ms
Frequency Filter Type Constant
Single compartment, abstract, or point cells do not have morphology data.
Complexity Summary
Relative Complexity 0.41 HH
State Equations 2
Optimal Time-Step 0.03324 ms
Model Size
Sections 1
Compartments 1
State Equations 2
Variable Time-Step Complexity
CVODE Steady State Step Frequency 1801 Hz
CVODE Steps Per AP 621
CVODE Benchmark Run Time 0.41 HH
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