Purkinje Cell

Model Type:
Cell
Neurolex IDs: Cerebellum Purkinje cell, Cerebellar, Purkyne, Corpuscles
Keywords: Rat, Active Dendrites, Purkinje Cell, Fast Somatic Spikes, Dendritic Calcium Spikes, Plateau Potentials
Publication: De Schutter & Bower (1994) An active membrane model of the cerebellar Purkinje cell. I. Simulation of current clamps in slice
Authors:
Erik De Schutter   James Bower  
Translators: Padraig Gleeson   Arnd Roth   David Beeman  
Sources:
Files:
Model ID NeuroML File
NMLCL000005
purk2.cell.nml
( view NeuroML )
NMLCH000027
Leak.channel.nml
( view NeuroML )
Notes: This NeuroML translation has only passive channels. See: https://github.com/OpenSourceBrain/PurkinjeCell/issues
Model Id: NMLCL000005
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Abstract Spiking (AS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive Yes
Is Intrinsically Spiking No
Resting Voltage -80.00 mV
Rheobase Current Interval (N/A, N/A] nA
Threshold Current Interval (N/A, N/A] nA
Bias Current (to N/A mV) N/A nA
Testing Temperature 37.0 °C
Stability Interval [-10.0, 15.0] nA
AP 1-2 Amplitude Drop N/A mV
AP 1 Steady State Amplitude Change N/A mV
AP 1 Amplitude N/A mV
AP 1 Width at Half Height N/A ms
AP 1 Width (Peak To Trough) N/A ms
AP 1 Rate of Change Peak to Trough N/A mV/ms
AP 1 AHP Depth N/A mV
AP2 Amplitude N/A mV
AP2 Width at Half Height N/A ms
AP 2 Width (Peak to Trough) N/A ms
AP 2 Rate of Change Peak to Trough N/A mV/ms
AP 2 AHP Depth N/A mV
AP 1-2 Amplitude Change Percent N/A %
AP 1-2 Half Width Change Percent N/A %
AP 1-2 Rate of Change Peak to Trough Percent Change N/A %
AP 1-2 AHP Depth Percent Change N/A %
Input Resistance N/A MΩ
AP 1 Delay Mean N/A ms
AP 1 Delay SD N/A ms
AP 2 Delay Mean N/A ms
AP 2 Delay SD N/A ms
Burst 1 ISI Mean N/A ms
Burst 1 ISI SD N/A ms
Initial Accommodation Mean N/A %
Steady State Accommodation Mean N/A %
Accommodation Rate to Steady State N/A %/ms
Accommodation at Steady State Mean N/A %
Accommodation Rate Mean at Steady State N/A ms
ISI CV N/A
ISI Median N/A ms
ISI Burst Mean Change N/A %
Spike Rate (Strong Stimulation) N/A Hz
AP 1 Delay Mean (Strong Stimulation) N/A ms
AP 1 Delay SD (Strong Stimulation) N/A ms
AP 2 Delay Mean (Strong Stimulation) N/A ms
AP 2 Delay SD (Strong Stimulation) N/A ms
Burst 1 ISI Mean (Strong Stimulation) N/A ms
Burst 1 ISI SD (Strong Stimulation) N/A ms
Ramp First Spike Time N/A ms
Frequency Filter Type N/A
Frequency Filter Pass Above N/A Hz
Frequency Filter Pass Below N/A Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 83137.8 µm2
Number of Stems 1.0
Number of Bifurcations 473.0
Number of Branches 947.0
Overall Width 260.169 µm
Overall Height 282.228 µm
Overall Depth 27.31 µm
Average Diameter 1.92686 µm
Total Length 12889.2 µm
Total Surface 74164.4 µm2
Total Volume 64136.8 µm3
Max Euclidean Distance 302.406 µm
Max Path Distance 370.298 µm
Max Branch Order 29.0
Average Contraction 0.94831
Total Fragmentation 2140.0
Partition Asymmetry 0.507011
Average Rall's Ratio 2.91554
Average Bifurcation Angle Local 51.5264 °
Average Bifurcation Angle Remote 57.4753 °
Fractal Dimension 1.02221
Complexity Summary
State Equations 1600
Optimal Time-Step N/A ms
Relative Complexity N/A HH
Model Size
Sections 1600
Compartments 1600
State Equations 1600
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step N/A ms
Optimal Time-Step Error N/A %
Optimal Time-Step Benchmark Run Time N/A HH
 
Maximum Stable Time-Step N/A ms
Maximum Stable Time-Step Error N/A %
Max. Stable Time-Step Benchmark Run Time N/A HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency N/A Hz
CVODE Steps Per AP N/A
CVODE Benchmark Run Time N/A HH
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