CA1 Pyramidal Cell

Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -65.00 mV
Rheobase Current Interval (0.75531, 0.76103] nA
Threshold Current Interval (1.40625, 1.46484] nA
Bias Current (to -80.00 mV) -1.3807 nA
Testing Temperature 35.0 °C
Stability Interval [-8.4375, 15.0] nA
AP 1-2 Amplitude Drop 2.3904 mV
AP 1 Steady State Amplitude Change 2.2006 mV
AP 1 Amplitude 74.8610 mV
AP 1 Width at Half Height 0.8200 ms
AP 1 Width (Peak To Trough) 1.7000 ms
AP 1 Rate of Change Peak to Trough -49.8209 mV/ms
AP 1 AHP Depth 9.8346 mV
AP2 Amplitude 72.4705 mV
AP2 Width at Half Height 0.8200 ms
AP 2 Width (Peak to Trough) 1.8300 ms
AP 2 Rate of Change Peak to Trough -44.6128 mV/ms
AP 2 AHP Depth 9.1709 mV
AP 1-2 Amplitude Change Percent -3.1932 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -10.4537 %
AP 1-2 AHP Depth Percent Change -6.7487 %
Input Resistance 10.4757 MΩ
AP 1 Delay Mean 5.0700 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 18.0200 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 13.4900 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -3.5714 %
Steady State Accommodation Mean -3.5714 %
Accommodation Rate to Steady State -0.1114 %/ms
Accommodation at Steady State Mean -11.3006 %
Accommodation Rate Mean at Steady State 13.8660 ms
ISI CV 95.8173
ISI Median 14.6000 ms
ISI Burst Mean Change 8.3398 %
Spike Rate (Strong Stimulation) 2.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 1.5500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 6.9200 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 5.4650 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2108.0100 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 29.3674 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 1320.59 µm2
Number of Stems 4.0
Number of Bifurcations 85.0
Number of Branches 173.0
Overall Width 218.975 µm
Overall Height 680.505 µm
Overall Depth 133.34 µm
Average Diameter 1.48467 µm
Total Length 12044.8 µm
Total Surface 55248.2 µm2
Total Volume 21324.8 µm3
Max Euclidean Distance 579.57 µm
Max Path Distance 658.921 µm
Max Branch Order 22.0
Average Contraction 0.923966
Total Fragmentation 2245.0
Partition Asymmetry 0.517161
Average Rall's Ratio 2.34192
Average Bifurcation Angle Local 60.7583 °
Average Bifurcation Angle Remote 41.9231 °
Fractal Dimension 1.01993
Complexity Summary
State Equations 27019
Optimal Time-Step 0.00553 ms
Relative Complexity 13651.82 HH
Model Size
Sections 173
Compartments 3008
State Equations 27019
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00553 ms
Optimal Time-Step Error 1.97 %
Optimal Time-Step Benchmark Run Time 13651.82 HH
 
Maximum Stable Time-Step 0.03125 ms
Maximum Stable Time-Step Error 4.24 %
Max. Stable Time-Step Benchmark Run Time 37705.92 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 13583 Hz
CVODE Steps Per AP 373
CVODE Benchmark Run Time 8587.75 HH
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